Biochemistry
9th Edition
ISBN: 9781305961135
Author: Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher: Cengage Learning
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Chapter 17, Problem 11RE
REFLECT AND APPLLY In what way is the observed mode of action of hexokinase consistent with the induced-fit theory of enzyme action?
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Chapter 17 Solutions
Biochemistry
Ch. 17 - RECALL Which reaction or reactions that we have...Ch. 17 - RECALL Which reaction or reactions that we have...Ch. 17 - RECALL What are the possible metabolic fates of...Ch. 17 - RECALL Explain the origin of the name of the...Ch. 17 - RECALL Define isozymes and give an example from...Ch. 17 - RECALL Why would enzymes be found as isozymes?Ch. 17 - RECALL Why is the formation of...Ch. 17 - REFLECT AND APPLLY Show that the reaction...Ch. 17 - REFLECT AND APPLLY What is the metabolic advantage...Ch. 17 - REFLECT AND APPLLY What are the metabolic effects...
Ch. 17 - REFLECT AND APPLLY In what way is the observed...Ch. 17 - REFLECT AND APPLLY How does ATP act as an...Ch. 17 - RECALL At what point in glycolysis are all the...Ch. 17 - RECALL Which of the enzymes discussed in this...Ch. 17 - RECALL Define substrate-level phosphorylation and...Ch. 17 - Prob. 16RECh. 17 - RECALL Which molecules act as inhibitors of...Ch. 17 - RECALL Many NADH-linked dehydrogenases have...Ch. 17 - RECALL Several of the enzymes of glycolysis fall...Ch. 17 - Prob. 20RECh. 17 - REFLECT AND APPLLY Is the reaction of...Ch. 17 - Prob. 22RECh. 17 - Prob. 23RECh. 17 - Prob. 24RECh. 17 - Prob. 25RECh. 17 - Prob. 26RECh. 17 - Prob. 27RECh. 17 - Prob. 28RECh. 17 - RECALL If lactic acid is the buildup product of...Ch. 17 - Prob. 30RECh. 17 - Prob. 31RECh. 17 - Prob. 32RECh. 17 - REFLECT AND APPLLY What is unique about TPP that...Ch. 17 - BIOCHEMICAL CONNECTIONS Beriberi is a disease...Ch. 17 - REFLECT AND APPLLY Most hunters know that meat...Ch. 17 - REFLECT AND APPLLY What is the metabolic advantage...Ch. 17 - BIOCHEMICAL CONNECTIONS Cancer cells grow so...Ch. 17 - Prob. 38RECh. 17 - Prob. 39RECh. 17 - REFLECT AND APPLLY Show how the estimate of 33%...Ch. 17 - Prob. 41RECh. 17 - Prob. 42RECh. 17 - Prob. 43RECh. 17 - Prob. 44RECh. 17 - REFLECT AND APPLLY Show, by a series of equations,...Ch. 17 - REFLECT AND APPLLY What should be the net ATP...Ch. 17 - Prob. 47RECh. 17 - Prob. 48RECh. 17 - Prob. 49RECh. 17 - REFLECT AND APPLLY According to Table 17.1,...Ch. 17 - Prob. 51RECh. 17 - Prob. 52RECh. 17 - REFLECT AND APPLLY High levels of...Ch. 17 - Prob. 54RECh. 17 - Prob. 55RE
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- REFLECT AND APPLY A model is proposed to explain the reaction catalyzed by an enzyme. Experimentally obtained rate data fit the model to within experimental error. Do these findings prove the model?arrow_forwardREFLECT AND APPLY Would nature rely on the same enzyme to catalyze a reaction either way (forward or backward) if the DG were 0.8kcalmol1? If it were 5.3kcalmol1?arrow_forwardREFLECT AND APPLY Explain how the pentose phosphate path- way can respond to a cells need for ATP, NADPH, and ribose-5- phosphate.arrow_forward
- REFLECT AND APPLY In the mitochondrion is a short-chain carnitine acyltransferase that can take acetyl groups from acetyl-CoA and transfer them to carnitine. How might this be related to lipid biosynthesis?arrow_forwardREFLECT AND APPLLY What is the metabolic advantage in the conversion of glucose to lactate, in which there is no net oxidation or reduction?arrow_forwardREFLECT AND APPLY How would it affect the reactions of the pentose phosphate pathway to have an epimerase and not an isomerase to catalyze the reshuffling reactions?arrow_forward
- REFLECT AND APPLY (a) Where in an earlier chapter have we en- countered something comparable to the action of the acyl carrier protein (ACP) of fatty acid synthesis? (b) What is a critical feature of the action of the ACP?arrow_forwardREFLECT AND APPLY When we compare the binding of I and of S to the enzyme in a mixed noncompetitive inhibitor, we assumed that the binding of I decreased the affinity of the enzyme for S. What would happen if the opposite were true?arrow_forwardREFLECT AND APPLY Why can we say that having a pure non- competitive inhibitor present is similar to just having less enzyme present?arrow_forward
- RECALL Show graphically how the reaction velocity depends on the enzyme concentration. Can a reaction be saturated with enzyme?arrow_forwardREFLECT AND APPLY Would you expect an irreversible inhibitor of an enzyme to be bound by covalent or by non-covalent interactions? Why?arrow_forwardREFLECT AND APPLY Suggest a reason why heating a solution containing an enzyme markedly decreases its activity. Why is the decrease of activity frequently much less when the solution contains high concentrations of the substrate?arrow_forward
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