Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 17, Problem 20P
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A recently married couple are both heterozygous for cystic fibrosis, a recessive genetic disorder. They would like to start a family and would like to have two children.
a.) What is the probability that their second pregnancy would result in a child with cystic fibrosis?
b.) What is the probability that their second pregnancy would result in a child with cystic fibrosis?
If a Mother's genotype is IAi and her Daughter's genotype is ii and the mother claims a man who is type B as the father...
a) Is that possible? Explain.
b) The accused man can prove that both of his parents are type AB. Is it possible for him to be type B? If so, what is his genotype? Explain.
d) Does the answer in part c change the answer in part b? Explain.
Chapter 17 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 17 - 17.1 Reciprocal crosses of experimental animals or...Ch. 17 - 17.2 How are some of the characteristics of the...Ch. 17 - 17.3 The human mitochondrial genome encodes...Ch. 17 - What is the evidence that transfer of DNA from the...Ch. 17 - Draw a graph depicting the relative amounts of...Ch. 17 - Prob. 6PCh. 17 - 17.7 What is the evidence that the ancient...Ch. 17 - 17.8 Outline the steps required for a gene...Ch. 17 - 17.9 Consider the phylogenetic tree presented in...Ch. 17 - You are a genetic counselor, and several members...
Ch. 17 - A mutation in Arabidopsis immutans results in the...Ch. 17 - What type or types of inheritance are consistent...Ch. 17 - You have isolated (1) a streptomycin-resistant...Ch. 17 - You have isolated two petite mutants, pet1 and...Ch. 17 - 17.15 Consider this human pedigree for a vision...Ch. 17 - A 50- year - old man has been diagnosed with MELAS...Ch. 17 - 17.17 The first person in a family to exhibit...Ch. 17 - Prob. 18PCh. 17 - 17.19 What is the most likely mode of inheritance...Ch. 17 - 17.20 In , the Russian Tsar Nicholaswas deposed,...Ch. 17 - 17.21 The dodo bird (Raphus cucullatus) lived on...Ch. 17 - Cytoplasmic male sterility (CMS) in plants has...Ch. 17 - 17.23 Wolves and coyotes can interbreed in...Ch. 17 - Prob. 24PCh. 17 - Prob. 25PCh. 17 - Most large protein complexes in mitochondria and...Ch. 17 - As described in this chapter, mothers will pass on...
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- b) Figure 2 shows a family tree in which the blood group of certain individuals have been identified. 6. Figure 2 i) Identify the blood group of individual 2 and state your reason. ii) If Individual 6 marries a woman with the same blood group, state the phenotype of their children. iii) If Individual 6 has the same genotype with his grandfather, give the genotype of individual 5.arrow_forwardHow is it possible Jonathan has the dominant disorder, Huntington’s Disease, if none of his family had it? a) The mutant allele remained ‘hidden’ in previous generations. b) He is homozygous for mutant huntingtin alleles unlike his grandparents, who are clearly heterozygous for the condition. c) The appearance of Huntington Disease in him might be the result of a new mutation appearing during his lifetime. d) His parents and grandparents were ashamed to admit they had it.arrow_forwardIdentify the sex and any genetic conditions by analyzing the karyotype of this individual. 1.a) male b) female 2. a) normal b) triploid c) patau d) edwards syndrome e) down syndrome f) triplo-X g) turners syndrome h) klinefelter syndromearrow_forward
- Tony has a sister with cystic fibrosis (CF). Neither of his parents have CF, nor does Tony. Tony is expecting a child with Tina. Tina does not have CF, but otherwise her family history is unknown. A) What is the probability that Tony is heterozygous for the CF gene? B) If the frequency of heterozygotes in the general population is 1/50, what is the probability that Tony and Tina's child will have CF?arrow_forwardDescendants of Queen Victoria (1819-1901) of England is believed to have suffered from hemophilia B, otherwise known as Christmas disease. Suppose that her affected son married her carrier daughter, what would be the chances of having a normal child? (A) 0% (B) 25% (C) 50% (D) 75%arrow_forwardA man and a woman have a child with cystic fibrosis. Neither parent has cystic fibrosis. How could this happen? a) Both parents carry the cystic fibrosis allele, and each passed that allele to their child. b) The child had a spontaneous mutation on both copies of their CFTR alleles, leading to cystic fibrosis. c) One parent gave the child two copies of the cystic fibrosis CFTR allele. c) One parent gave the child a wild type CFTR allele, and the other parent gave them a cystic fibrosis CFTR gene.arrow_forward
- 2) You're the director of Foothill Presbyterian Hospital's maternity ward, and you have four mixed-up babies, with blood types of O, A, B, and AB. The four sets of desperate parents are threatening to sue you if you don't get their babies back. You know the blood types (phenotypes) of the parents are: i) AB and O ii) A and O iii) A and AB iv) O and O You also know that each set of parents has only one child (no sets of twins, that is). Match each baby with its parents.arrow_forwardI will be adding two questions here because I asked two of the same questions twice by accident earlier. A man and a woman do not have hemophilioa, but the womans father did. (Hemophilia is X-linked recessive). a) What is the probability that they will have a child with hemophilia? b) Is it possible for any of their daughters to be affected? Explain. A cross between a horse homozygous for red hair and a horse homozygous for white hair results in offspring with the coat colour called roan. When you look at the fur of the roan offspring you see both red and white hairs. What type of inheritance best explains this? a) blending inheritance b)codominance c)incomplete codominance d)multiple allelesarrow_forwardMrs Mumba delivered a baby girl in a certain hospital. Mrs Mumba has blood group O and the father to the girl has blood group AB. Mrs Mumba sues the hospital for giving her a wrong baby whose blood group was 0. (a) Explain using a genetic diagram why Mrs Mumba would win or lose the case. (b) What could have been the correct genotype of the actual father?arrow_forward
- Cystic Fibrosis (CF) is an autosomal recessive condition. Therefore, heterozygous (Cc) carriers do not display symptoms. Two parents who are carriers plan to start a family and you are a genetic counselor helping to advise them about their chances of having children affected by CF. a) Suppose the couple has 4 children, each one year apart. What is the probability that all 4 children will inherit CF? b) What is the probability that any 3 of their 4 children will not inherit CF, but 1 will be affected? c) What is the probability that their first child will not inherit CF, but the younger 3 children will inherit CF?arrow_forwardPKU is an inherited disease caused by a recessive allele. If a woman and her husband, who are both carriers (heterozygotes) for the disorder, have three children, what is the probability of each of the following? a) All three children are of normal phenotype. b) All three children have the disease. c) Any 2 of the three children have the normal phenotype.arrow_forwardShown below is a pedigree for Phenylketonuria (PKU), an autosomal recessive metabolic disorder. The characteristic feature of PKU is severe mental retardation A) What is the probability that individual II-1 is heterozygous for this gene? B) What is the probability that individual III-4 is heterozygous for this gene? C) If individuals III-3 and III-4 were to marry, what is the probability that their child would express PKU?arrow_forward
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY