Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 17, Problem 18P
Summary Introduction

To analyze:

Pedigree given in which many members of family show symptoms of mitochondrial disease MERRF. Analyze the chance of -2 and -5 children being affected with MERRF.

Introduction:

In sexually reproducing organisms like mammals, the egg cell usually destroys the sperm after fertilization. The contribution from a diploid zygote is only haploid set of chromosomes. The Fetus receives other the cellular components from the mother’s side (Egg). Thus, the diseases related to mitochondria are maternally inherited. Mitochondrial disease is not passed to the next generation from the paternal side.

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Chapter 17 Solutions

Genetic Analysis: An Integrated Approach (3rd Edition)

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY