A detail mechanism for the formation of Z-Ala is to written, reason for the amino group act as the nucleophile preferentially over the carboxylate anion to be explained and the mechanism for formation of Fmoc-protected amino under the given condition is to be written. Concept introduction: The essence of the peptide of protein synthesis is formation of the amide function group by the reaction of an activated carboxylic acid derivative with an amine . The Fmoc (fluorenymethyloxycarbonyl) acts as a base-labile protecting group.

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Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 17, Problem 1LGP

Interpretation Introduction

Interpretation:

A detail mechanism for the formation of Z-Ala is to written, reason for the amino group act as the nucleophile preferentially over the carboxylate anion to be explained and the mechanism for formation of Fmoc-protected amino under the given condition is to be written.

Concept introduction:

The essence of the peptide of protein synthesis is formation of the amide function group by the reaction of an activated carboxylic acid derivative with an amine.

The Fmoc (fluorenymethyloxycarbonyl) acts as a base-labile protecting group.

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What initiates a dehydration process between two amino acids, provided their carboxyl groups are exactly aligned with the amine groups of the other?

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 17, Problem 1LGP

Interpretation Introduction

Interpretation:

A detail mechanism for the formation of Z-Ala is to written, reason for the amino group act as the nucleophile preferentially over the carboxylate anion to be explained and the mechanism for formation of Fmoc-protected amino under the given condition is to be written.

Concept introduction:

The essence of the peptide of protein synthesis is formation of the amide function group by the reaction of an activated carboxylic acid derivative with an amine.

The Fmoc (fluorenymethyloxycarbonyl) acts as a base-labile protecting group.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 17, Problem 1LGP

Interpretation Introduction

Interpretation:

A detail mechanism for the formation of Z-Ala is to written, reason for the amino group act as the nucleophile preferentially over the carboxylate anion to be explained and the mechanism for formation of Fmoc-protected amino under the given condition is to be written.

Concept introduction:

The essence of the peptide of protein synthesis is formation of the amide function group by the reaction of an activated carboxylic acid derivative with an amine.

The Fmoc (fluorenymethyloxycarbonyl) acts as a base-labile protecting group.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 17, Problem 1LGP

Interpretation Introduction