Use the image to answer the question. AMP-PNP is a non-hydrolyzable ATP analog that cannot be metabolized by cells. Taurocholate is a bile acid that helps emulsify fats. When taurocholate is added to hepatocyte cell culture, it accumulates in those cells. The graph below shows the rate of cellular accumulation of the drug taurocholate in the presence of either no ATP, ATP, or AMP-PNP. Based on this data, describe the mechanism by which taurocholate enters the cell. Justify your answer.
Use the image to answer the question. AMP-PNP is a non-hydrolyzable ATP analog that cannot be metabolized by cells. Taurocholate is a bile acid that helps emulsify fats. When taurocholate is added to hepatocyte cell culture, it accumulates in those cells. The graph below shows the rate of cellular accumulation of the drug taurocholate in the presence of either no ATP, ATP, or AMP-PNP. Based on this data, describe the mechanism by which taurocholate enters the cell. Justify your answer.
Anatomy & Physiology
1st Edition
ISBN:9781938168130
Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Chapter19: The Cardiovascular System: The Heart
Section: Chapter Questions
Problem 35CTQ: Why is afterload important to cardiac function?
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Use the image to answer the question.
AMP-PNP is a non-hydrolyzable ATP analog that cannot be
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no ATP
ATP
AMP-PNP
pmol/mg/min](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F5b19c472-d58f-4c80-85c0-1f98bcd18771%2Fe49f82ee-6fa9-4fc6-8e3b-bce725cb75d2%2Fpcfce1zq_processed.png&w=3840&q=75)
Transcribed Image Text:40
30
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no ATP
ATP
AMP-PNP
pmol/mg/min
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