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Which of the following is true of the difference between Class I and Class II B-lactamase inhibitors? 1. Class I inhibitors do not have a heteroatom leaving group at position 1 2. Class II inhibitors are useful in combination with extended spectrum penicillins to broaden their spectrum of activities 3. Examples of Class I inhibitors are Thienamycin, Imipenem and Ertapenem 4. Class II inhibitors have potent antibacterial activity in addition to transient inhibition of B-lactamases 01 2 0 3

Which of the following is true of the difference between Class I and Class II B-lactamase inhibitors? 1. Class I inhibitors do not have a heteroatom leaving group at position 1 2. Class II inhibitors are useful in combination with extended spectrum penicillins to broaden their spectrum of activities 3. Examples of Class I inhibitors are Thienamycin, Imipenem and Ertapenem 4. Class II inhibitors have potent antibacterial activity in addition to transient inhibition of B-lactamases 01 2 0 3

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Which of the following is true of the difference between Class I and Class II B-lactamase inhibitors? 1. Class I inhibitors do not have a heteroatom leaving group at position 1 2. Class II inhibitors are useful in combination with extended spectrum penicillins to broaden their spectrum of activities 3. Examples of Class I inhibitors are Thienamycin, Imipenem and Ertapenem 4. Class Il inhibitors have potent antibacterial activity in addition to transient inhibition of B-lactamases O 1 O 3 4
Transcribed Image Text:Which of the following is true of the difference between Class I and Class II B-lactamase inhibitors? 1. Class I inhibitors do not have a heteroatom leaving group at position 1 2. Class II inhibitors are useful in combination with extended spectrum penicillins to broaden their spectrum of activities 3. Examples of Class I inhibitors are Thienamycin, Imipenem and Ertapenem 4. Class Il inhibitors have potent antibacterial activity in addition to transient inhibition of B-lactamases O 1 O 3 4
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