This pedigree illustrates the pattern of inheritance of a fully penetrant autosomal dominant trait in a large human family. This trait is linked to a SNP marker with 3 alleles (A, B and C). Under each pedigree symbol there is an individual number followed by this individual's SNP genotype in parentheses. (a). Which individuals in this pedigree inherited a chromosome we can identify as recombinant or non-recombinant? (b). Of those who could inherit a recombinant chromosome, which individual(s) did? (c). What recombination frequency between the dominant trait gene and the SNP marker is indicated by these data? Express your answer as a fraction.
This pedigree illustrates the pattern of inheritance of a fully penetrant autosomal dominant trait in a large human family. This trait is linked to a SNP marker with 3 alleles (A, B and C). Under each pedigree symbol there is an individual number followed by this individual's SNP genotype in parentheses. (a). Which individuals in this pedigree inherited a chromosome we can identify as recombinant or non-recombinant? (b). Of those who could inherit a recombinant chromosome, which individual(s) did? (c). What recombination frequency between the dominant trait gene and the SNP marker is indicated by these data? Express your answer as a fraction.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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