This pedigree illustrates the pattern of inheritance of a fully penetrant autosomal dominant trait in a large human family. This trait is linked to a SNP marker with 3 alleles (A, B and C). Under each pedigree symbol there is an individual number followed by this individual's SNP genotype in parentheses. (a). Which individuals in this pedigree inherited a chromosome we can identify as recombinant or non-recombinant? (b). Of those who could inherit a recombinant chromosome, which individual(s) did? (c). What recombination frequency between the dominant trait gene and the SNP marker is indicated by these data? Express your answer as a fraction.
This pedigree illustrates the pattern of inheritance of a fully penetrant autosomal dominant trait in a large human family. This trait is linked to a SNP marker with 3 alleles (A, B and C). Under each pedigree symbol there is an individual number followed by this individual's SNP genotype in parentheses. (a). Which individuals in this pedigree inherited a chromosome we can identify as recombinant or non-recombinant? (b). Of those who could inherit a recombinant chromosome, which individual(s) did? (c). What recombination frequency between the dominant trait gene and the SNP marker is indicated by these data? Express your answer as a fraction.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:6).
Generation I
IV
1(A,A)
1(C,C) 2(A,B)
2(B,C)
3(A,C) 4(B,B)
Page
<
3(A,C)
6
5(A,B)
of 6
1(A,A) 2(B,C) 3(B,C) 4(B,C) 5(B,C) 6(A,B) 7(A,B) 8(C,C) 9(B,B) 10(A,B)
Ō
1(A,C) 2(A,B)
6(B,B)
This pedigree illustrates the pattern of inheritance of a fully penetrant autosomal dominant trait in a
large human family. This trait is linked to a SNP marker with 3 alleles (A, B and C). Under each pedigree
symbol there is an individual number followed by this individual's SNP genotype in parentheses.
(b). Of those who could inherit a recombinant chromosome, which individual(s) did?
(a). Which individuals in this pedigree inherited a chromosome we can identify as recombinant or
non-recombinant?
(c). What recombination frequency between the dominant trait gene and the SNP marker is
indicated by these data? Express your answer as a fraction.
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+
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