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A woman, seeking genetic counseling, is found to be heterozygous for a chromosomal rearrangement between the 2nd and 3rd chromosomes. Her chromosomes, compared to those in a normal karyotype, are diagrammed here: A E A E B F B LL F 0 0 G C D D H H CHROMO.: 2 2/3 2/3 3 a. What kind of chromosomal aberration is shown? b. Using a drawing, demonstrate how these chromosomes would pair during meiosis. c. This woman has had two miscarriages. She has come to you, an established genetic counselor. She raises the ff. questions: Provide an informed response to her concerns: Is there a genetic explanation of her frequent miscarriages? • Should she abandon her attempts to have a child of her own? If not, what is the chance that she could have a normal child?

A woman, seeking genetic counseling, is found to be heterozygous for a chromosomal rearrangement between the 2nd and 3rd chromosomes. Her chromosomes, compared to those in a normal karyotype, are diagrammed here: A E A E B F B LL F 0 0 G C D D H H CHROMO.: 2 2/3 2/3 3 a. What kind of chromosomal aberration is shown? b. Using a drawing, demonstrate how these chromosomes would pair during meiosis. c. This woman has had two miscarriages. She has come to you, an established genetic counselor. She raises the ff. questions: Provide an informed response to her concerns: Is there a genetic explanation of her frequent miscarriages? • Should she abandon her attempts to have a child of her own? If not, what is the chance that she could have a normal child?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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A woman, seeking genetic counseling, is found to be heterozygous for a chromosomal rearrangement between the 2nd and 3rd chromosomes. Her chromosomes, compared to those in a normal karyotype, are diagrammed here: A E A E B F B LL F 0 0 G C D D H H CHROMO.: 2 2/3 2/3 3 a. What kind of chromosomal aberration is shown? b. Using a drawing, demonstrate how these chromosomes would pair during meiosis. c. This woman has had two miscarriages. She has come to you, an established genetic counselor. She raises the ff. questions: Provide an informed response to her concerns: Is there a genetic explanation of her frequent miscarriages? • Should she abandon her attempts to have a child of her own? If not, what is the chance that she could have a normal child?
Transcribed Image Text:A woman, seeking genetic counseling, is found to be heterozygous for a chromosomal rearrangement between the 2nd and 3rd chromosomes. Her chromosomes, compared to those in a normal karyotype, are diagrammed here: A E A E B F B LL F 0 0 G C D D H H CHROMO.: 2 2/3 2/3 3 a. What kind of chromosomal aberration is shown? b. Using a drawing, demonstrate how these chromosomes would pair during meiosis. c. This woman has had two miscarriages. She has come to you, an established genetic counselor. She raises the ff. questions: Provide an informed response to her concerns: Is there a genetic explanation of her frequent miscarriages? • Should she abandon her attempts to have a child of her own? If not, what is the chance that she could have a normal child?
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