A genetic disorder is caused by a LOF mutation (Bm) and epigenetic imprinting of gene B. Through pedigree analysis of many families, researchers have observed the following results: Female carrier B+Bm x B+B+ --> B+Bm and Mother's genotypeFather's genotypeChildren's genotypeChildren's phenotypeCross 1:B+BmB+B+B+Bm , B+B+some affected, some unaffectedCross 2: B+B+B+BmB+Bm , B+B+always unaffectedBased on these results, gene B is imprinted on the:a. maternalb. paternal

Name: A genetic disorder is caused by a LOF mutation (Bm) and epigenetic imp
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Description: A genetic disorder is caused by a LOF mutation (Bm) and epigenetic imprinting of gene B. Through pedigree analysis of many families, researchers have observed the following results: Female carrier B+Bm x B+B+ --> B+Bm and Mother's genotypeFather's g

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Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

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A genetic disorder is caused by a LOF mutation (B^m) and epigenetic imprinting of gene B. Through pedigree analysis of many families, researchers have observed the following results:

Female carrier B⁺B^m x B⁺B⁺ --> B⁺B^mand

	Mother's genotype	Father's genotype	Children's genotype	Children's phenotype
Cross 1:	B⁺B^m	B⁺B⁺	B⁺B^m, B⁺B⁺	some affected, some unaffected
Cross 2:	B⁺B⁺	B⁺B^m	B⁺B^m, B⁺B⁺	always unaffected

Based on these results, gene B is imprinted on the:

a. maternal

b. paternal

Expert Solution

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Epigenetic imprinting or genomic imprinting is a process where there is the exclusive expression of some specific genes from one parent only. It involves DNA methylation and histone methylation.

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