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To determine the number of genes potentially involved in eye development in mouse, you perform a screen of mutant mice (having no eyes). You isolate 10 strains of mouse with no eyes (Line 1 to Line 10) each of which are homozygous recessive). You then perform crosses between all strains and obtain the following results where phenotype represents offspring with eyes. The “??" are not known at this time. phenotype indicates mouse without eyes and a “+" Line 1 Line 2 Line 3 Line 4 Line 5 Line 6 Line 7 Line 8 Line 9 Line 10 Line 1 Line 2 Line 3 + ?? Line 4 + + + Line 5 + ?? + Line 6 + + + Line 7 + ?? + ?? Line 8 ?? + + + + + Line 9 + + + + + + Line 10 + + + + Wild - + + + + + + + + + type a. Based on the data, i) determine the complementation groups and ii) the number of genes potentially involved in the production of eyes in mice? b. Based on the data available, determine if the following crosses will produce mice with eyes or without eyes: Line 3 X Line 5 : Line 6 X Line 7 : Line 3 X Line7 : Line 1 X Line 8 : -: + E:

To determine the number of genes potentially involved in eye development in mouse, you perform a screen of mutant mice (having no eyes). You isolate 10 strains of mouse with no eyes (Line 1 to Line 10) each of which are homozygous recessive). You then perform crosses between all strains and obtain the following results where phenotype represents offspring with eyes. The “??" are not known at this time. phenotype indicates mouse without eyes and a “+" Line 1 Line 2 Line 3 Line 4 Line 5 Line 6 Line 7 Line 8 Line 9 Line 10 Line 1 Line 2 Line 3 + ?? Line 4 + + + Line 5 + ?? + Line 6 + + + Line 7 + ?? + ?? Line 8 ?? + + + + + Line 9 + + + + + + Line 10 + + + + Wild - + + + + + + + + + type a. Based on the data, i) determine the complementation groups and ii) the number of genes potentially involved in the production of eyes in mice? b. Based on the data available, determine if the following crosses will produce mice with eyes or without eyes: Line 3 X Line 5 : Line 6 X Line 7 : Line 3 X Line7 : Line 1 X Line 8 : -: + E:

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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To determine the number of genes potentially involved in eye development in mouse, you perform a screen of mutant mice (having no eyes). You isolate 10 strains of mouse with no eyes (Line 1 to Line 10) each of which are homozygous recessive). You then perform crosses between all strains and obtain the following results where phenotype indicates mouse without eyes and a "+" phenotype represents offspring with eyes. The “??" are not known at this time. Line 1 Line 2 Line 3 Line 4 Line 5 Line 6 Line 7 Line 8 Line 9 Line 10 Line 1 Line 2 Line 3 + ?? Line 4 + + Line 5 ?? Line 6 + + + + Line 7 + ?? + ?? + Line 8 ?? + + + Line 9 + + + Line 10 + + + + Wild - + + + + + + + + type a. Based on the data, i) determine the complementation groups and ii) the number of genes potentially involved in the production of eyes in mice? b. Based on the data available, determine if the following crosses will produce mice with eyes or without eyes: Line 3 X Line 5 : Line 6 X Line 7 : Line 3 X Line7 : Line 1 X Line 8 :
Transcribed Image Text:To determine the number of genes potentially involved in eye development in mouse, you perform a screen of mutant mice (having no eyes). You isolate 10 strains of mouse with no eyes (Line 1 to Line 10) each of which are homozygous recessive). You then perform crosses between all strains and obtain the following results where phenotype indicates mouse without eyes and a "+" phenotype represents offspring with eyes. The “??" are not known at this time. Line 1 Line 2 Line 3 Line 4 Line 5 Line 6 Line 7 Line 8 Line 9 Line 10 Line 1 Line 2 Line 3 + ?? Line 4 + + Line 5 ?? Line 6 + + + + Line 7 + ?? + ?? + Line 8 ?? + + + Line 9 + + + Line 10 + + + + Wild - + + + + + + + + type a. Based on the data, i) determine the complementation groups and ii) the number of genes potentially involved in the production of eyes in mice? b. Based on the data available, determine if the following crosses will produce mice with eyes or without eyes: Line 3 X Line 5 : Line 6 X Line 7 : Line 3 X Line7 : Line 1 X Line 8 :
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