In the pedigree below, male II-1 has Klinefelter syndrome, which is the result of an XXY karyotype. On the X chromosome, a gene called G6PD has two codominant alleles, G6PDA and G6PDB. In this pedigree, A, B, and AB refer to the phenotypes associated with the alleles of this gene. (Note: In this family, no individuals have the AB version of the phenotype.) B A
In the pedigree below, male II-1 has Klinefelter syndrome, which is the result of an XXY karyotype. On the X chromosome, a gene called G6PD has two codominant alleles, G6PDA and G6PDB. In this pedigree, A, B, and AB refer to the phenotypes associated with the alleles of this gene. (Note: In this family, no individuals have the AB version of the phenotype.) B A
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Transcribed Image Text:In the pedigree below, male II-1 has Klinefelter syndrome, which is the
result of an XXY karyotype.
On the X chromosome, a gene called G6PD has two codominant
alleles, G6PDA and G6PDB. In this pedigree, A, B, and AB refer to the
phenotypes associated with the alleles of this gene. (Note: In this family,
no individuals have the AB version of the phenotype.)
A
A
B
Based on the information in the pedigree, when could nondisjunction
have occurred? Select all correct answers.
In Il-1's father, during meiosis I
In II-1's mother, during meiosis I
In II-1's mother, during meiosis II
In Il-1's father, during meiosis II
Expert Solution

Step 1
- Klinefelters syndrome occurs when an abnormal XY sperm fertilizes a normal X egg, or a normal Y sperm fertilizes a normal XX egg.
- It affects the males, and the affected male produces little or no sperm.
It also results in reduced muscle mass, gynecomastia, weaker bones, and small testicles.
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