boy with Klinefelter syndrome (47,XXY) is born to a mother who  is  phenotypically  normal  and  a  father who  has  the  X- linked  skin  condition  called  anhidrotic  ectodermal  dysplasia.  The boy has patches of normal skin and patches of abnormal skin. Which of the following statemnets likely explains these observations?   The father contributed the extra X chromosome in the son as a result of a non-disjunction in meiosis I during spermatogenesis. The mother contributed the extra X chromosome in the son as a result of a non-disjunction in meiosis II during oogenesis. The mother contributed the extra X chromosome in the son as a result of a non-disjunction in meiosis I during oogenesis. The father contributed the extra X chromosome in the son as a result of a non-disjunction in meiosis II during spermatogenesis. Either parent could have contributed to the extra X chromosome in the son as a results of disjunction in either meiosis I or meiosis II during gametogenesis.

Q: Trisomy 21, or Down syndrome, occurs when there is a normal diploid chromosomal complement but one…

A: Down's syndrome occurs due to an error at the time of gamete formation. As a result the gametes may…

Q: For the following chromosome complements, what is the phenotypic sex of a person who has Q. XXYY…

A: The male-determining gene in humans is termed as the sex determining region Y (SRY) gene. Generally…

Q: Glucose-6-phosphate dehydrogenase deficiency (G6PD) is inherited as an X-linked recessive gene in…

A: Glucose 6-phosphate dehydrogenase deficiency is inherited as an X-linked recessive gene. Woman has…

Q: Campomelic dysplasia (CMD1) is a congenital humansyndrome featuring malformation of bone and…

A: Campomelic dysplasia is a rare genetic disorder characterized by bowing of the long bones and many…

Q: A cross was performed between a female curly winged fly and a normal (straight) winged male fly.…

A: As per the question, a cross was performed between a female curly winged fly and a male straight…

Q: For the following chromosome complements, what is the phenotypic sex of a person who has Q. XO with…

A: The male sex-determining gene in human is termed as the sex determining region Y (SRY) gene.…

Q: Hemophilia results from a sex-linked gene. The disease is most common in males, but the hemophilia…

A:

Q: What is the percentage chance that individual V.2 , will have inherited the X-linked recessive…

A: X-linked recessive diseases are the diseases which  are passsed from the female carrier to males. So…

Q: Mr. and Mrs. Smith, both 40 years of age, are healthy with no knowngenetic conditions. Their newborn…

A: Down syndrome is defined as the condition in which an individual contains an extra chromosome. In…

Q: Mrs. Dee (40 years old) and her husband have an amniocentesis for advanced maternal age. They…

A: The amniocentesis is performed for the genetical analysis of the fetus. It helps in the early…

Q: In a sample of 1000 patients with Down syndrome, a geneticist discovers that 95% of them are…

A: Trisomy is a kind of polysomy in which three instances of a particular chromosome occurs. Generally…

Q: Two phenotypically normal parents produce a phenotypicallyabnormal child in which chromosome 5 is…

A: The thread-like structure present inside the nucleus is called a chromosome. The chromosome is…

Q: In general, why do changes in chromosome structure or numbertend to affect an individual’s…

A: Chromosome is a compact structure of a DNA molecule wrapped around some proteins. It is generally…

Q: karyotype is an important clinical method for diagnosing genetic disorders. Explain why it is useful…

A: A karyotype can be defined as a photograph of total chromosomes in a human body. It can be also said…

Q: Table 8.1 shows that Turner syndrome occurs when an individual inherits one X chromosome but lacks a…

A: Chromosomal deletion syndrome occurs when whole or part of chromosomes are missing. Turner Syndrome…

Q: The Klinefelter syndrome (disomy of the X chromosome in males) is a genetic disease caused by…

A: The normal humans contain 46 chromosomes. Between these 46 chromosomes, 44 are autosomes and 2 are…

Q: During the pathoanatomic inspection of a baby-boy's dead body the following abnormalities:…

A: Chromosomal disorder are the abnormalities that arises due to alterations in chromosome arrangement…

Q: Draw a Punnett square for the dihybrid cross. There are two known alleles of gene occupying a…

A: Dihybrid cross involves two genes in a cross. That's why the two traits are involved in this cross.

Q: A woman with no phenotype is known to have a 14:21 translocation. Please answer questions 1 and 2.…

A: Between two acrocentric chromosomes where the centromere is at one end of the…

Q: On rare occasions, people are born with a condition known as uniparental disomy. It happens when an…

A: Human contains two number of chromosomes 15, one inherited from mother (maternal) and one from…

Q: A family has an X-linked dominant form of congenital generalizedhypertrichosis (excessive…

A: Genes are the functional unit of DNA. It contains information that is transferred from one…

Q: Two phenotypically unaffected parents produce two children with familial Down syndrome. Regarding…

A: A phenotype is the observable physical and functional traits of an organism which result from the…

Q: The following Pedigree shows an unknown genetic disorder. The disorder is believed to be caused by…

A: In terms of genetics, a pedigree is a diagram demonstrating the manner in which a trait or medical…

Q: Both hemophilia (h) and favism (gd) are inherited as X-linked recessive traits. Hemophilia is an…

A: The alleles are the alternative forms of a gene that are located on the same locus of a homologous…

Q: For the following chromosome complements, what is the phenotypic sex of a person who has Q. XX with…

A: The sex-determining region Y (SRY) is located on the short branch of the Y chromosome, which…

Q: Primary oocytes in females are O dipoid and undergo mitosis O dplcid and undergo meiosis O haploid…

A: Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: Please answer question (a) (b) and (e)

A: Crossing over increases variations.

Q: Q1: How many male and how many female descendants (individuals that did not join the family by…

A: The traits that are present or absent in a family over generations are shown in a pedigree.I…

Q: Explain why a person with Klinefelter Syndrome (XXY) still exhibits abnormal phenotypes despite the…

A: The human sex is determined at the time of fertilization in the fallopian tube of the female…

Q: What is incomplete penetrance and what causes it?

A: Introduction  Any gene have two alleles pairs viz. Dominant or Recessive. The allele which gets…

Q: What kind of chromosomal mutations is/are produced by unequal crossing over?

A: Mutation refers to both the process of altering a gene or chromosome and the outcome of that…

Q: A woman is affected with Prader-Willi syndrome due to a deletion that includes both the Angelman…

A: Both the Prader-willi syndrome and Angelman syndrome is caused by deletion of of longer arm (q arm)…

Q: The gene causing Coffin-Lowry syndrome (OMIM 303600) was recently identified and mapped on the human…

A: Males and females of a species have separate sex chromosomes. The number of copies of seX-linked…

Q: Determine the patterns of inheritance of the following X-linked dominant cases by giving the results…

A: X Linked dominant inheritance means the genes present in X chromosomes, if the gene has dominant…

Q: Why does a single X chromosome cause infertility and other abnormalities in Turner Syndrome…

A: Turner syndrome (TS) is a genetic disorder that mostly affects females. The clinical features of…

Q: “carrier

A: X-linked inheritance means that the gene causing the trait or the disorder is located on the X…

Q: his area of the chromosome iIS 5%.

A: Introduction  Linkage disequilibrium (LD) is the nonrandom relationship of alleles of various loci.…

Q: Duchenne muscular dystrophy (DMD) is caused bya recessive mutant allele of an X-linked gene…

A: Duchenne muscular dystrophy (DMD) is a progressive form of muscular dystrophy that results in muscle…

Q: For the following chromosome complements, what is the phenotypic sex of a person who has Q. XXY with…

A: A gene is a unit of genetic material present within the DNA (deoxyribonucleic acid). Each gene…

Q: What kind of chromosomal mutations is/are produced by unequal crossing over?

A: Chromosome mutations are changes that arise in chromosomes as a result of nuclear division mistakes…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.