The gene causing Coffin-Lowry syndrome (OMIM 303600) was recently identified and mapped on the human Xchromosome. Coffin-Lowry syndrome is a rare disorder affecting brain morphology and development. It also producesskeletal and growth abnormalities, as well as abnormalities of motor control. Coffin-Lowry syndrome affects maleswho inherit a mutation of the X-linked gene. Most carrier females show no symptoms of the disease but a few carriersdo. These carrier females are always less severely affected than males. Offer an explanation for this finding.

Males and females of a species have separate sex chromosomes. The number of copies of seX-linked…

Answered: The gene causing Coffin-Lowry syndrome…

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