The following image shows a Robertsonian translocation between chromosomes 13 and 21. This has the potential to cause Down Syndrome in offspring. The couple had 6 pregnancies. What is the probable cause for the two miscarriages you see in the pedigree? See the legend for more information. Briefly explain your answer. male female miscarriage chromosome 13 chromosome 21 Robertsonian translocation Carrier Normal der(13;21)(q10;q10)

The following image shows a Robertsonian translocation between chromosomes 13 and 21. This has the potential to cause Down Syndrome in offspring. The couple had 6 pregnancies. What is the probable cause for the two miscarriages you see in the pedigree? See the legend for more information. Briefly explain your answer. male female miscarriage chromosome 13 chromosome 21 Robertsonian translocation Carrier Normal der(13;21)(q10;q10)

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations

Section: Chapter Questions

Problem 14QP: Variations in Chromosome NumberAneuploidy Describe the process of nondisjunction and explain when it...

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Compare meiotic anaphase I with meiotic anaphase II. Which meiotic anaphase is most similar to the mitotic anaphase?
People with Down syndrome have an extra copy of chromosome 21, for a total of 47 chromosomes. However, in a few cases of Down syndrome, 46 chromosomes are present. This total includes two normal-looking chromosomes 21, one normal chromosome 14, and a longer-than-normal chromosome 14. Interpret this observation. How can these individuals have 46 chromosomes?
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