The first reaction in Glycolysis is the phosphorylation of Glucose: Pi + Glucose → Glucose 6-Phosphate + water This is a thermodynamically unfavorable process with a ∆G0’ = +13.8 kJ/mol.  In a liver cell at 370C the concentrations of both phosphate and glucose are normally maintained at about 0.005 M each.  What would be the equilibrium concentration of Glucose 6-Phosphate according to the above data?  Note:  In the biochemical standard state ​[H2O] = 1.0 a. 0.00000012 b. 0.0000025 c. 0.00000025 d. 0.00474 e. 0.005 f. 1.0 g. 0.1 h. 0.25 i. 2.4

Biochemistry
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Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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The first reaction in Glycolysis is the phosphorylation of Glucose:
Pi + Glucose → Glucose 6-Phosphate + water
This is a thermodynamically unfavorable process with a ∆G0’ = +13.8 kJ/mol.  In a liver cell at
370C the concentrations of both phosphate and glucose are normally maintained at about 0.005 M each.  What would be the equilibrium concentration of Glucose 6-Phosphate according to the above data?  Note:  In the biochemical standard state ​[H2O] = 1.0

a. 0.00000012

b. 0.0000025

c. 0.00000025

d. 0.00474

e. 0.005

f. 1.0

g. 0.1

h. 0.25

i. 2.4

 

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