A clinical trial is conducted to compare an experimentalmedication to placebo to reduce the symptoms of asthma.Two hundred participants are enrolled in the study andrandomized to receive either the experimental medication orplacebo. The primary outcome is a self-reported reduction ofsymptoms. Among 100 participants who receive theexperimental medication, 38 report a reduction of symptomsas compared to 21 participants of 100 assigned to theplacebo.a. Generate a 95% CI for the difference in proportions ofparticipants reporting a reduction of symptoms betweenthe experimental and placebo groups. TABLE 6.25 Wound Healing by TreatmentTreatmentNew compound In = 125)Placebo (n=125)None412Number of Patients with Percent Reduction in Size of Wound26-50%51-75%373245341-25%1124Description76-100%4110

The objective of this question is to calculate the 95% confidence interval (CI) for the difference…

Answered: A clinical trial is conducted to…

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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True or False? A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. One hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 50 participants who receive the experimental medication, 30 report a reduction of symptoms as compared to 15 participants of 50 assigned to the placebo. The 95% CI for the relative risk of participants reporting a reduction of symptoms between the experimental and placebo groups is between 0.114 and 0.486.
A doctor is researching side effects with a new pain medication. A clinical trial including random sample of 340 people who took a new pain relief medication reveals that 23 suffered some side effects. At the .05 level of significance(α), is there evidence that greater than 10% of all patients who take the medication will experience side effects? a. 0.0468 b. 0.977 c. 0.0234 d. 0.0678
A deficiency of the trace element selenium in the diet can negatively impact growth, immunity, muscle and neuromuscular function, and fertility. The introduction of selenium supplements to dairy cows is justified when pastures have low selenium levels. Authors of a research paper supplied the following data on milk selenium concentration (mg/L) for a sample of cows given a selenium supplement (the treatment group) and a control sample given no supplement, both initially and after a 9-day period. Initial Measurement Treatment Control 11.4 9.1 9.6 8.7 10.1 9.7 8.5 10.8 10.2 10.9 10.6 10.6 11.9 10.1 9.9 12.3 10.7 8.8 10.2 10.4 10.3 10.9 11.4 10.4 9.3 11.6 10.6 10.9 10.9 8.3 After 9 Days Treatment Control 138.3 9.2 104 8.9 96.4 8.9 89 10.1 88 9.6 103.8 8.6 147.3 10.4 97.1 12.4 172.6 9.2 146.3 9.5 99 8.4 122.3 8.8 103 12.5 117.8 9.1 121.5 93 (a) Use the given data for the treatment group to determine if…
A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 100 participants who receive the experimental medication, 38 report a reduction of symptoms as compared to 21 participants of 100 assigned to placebo. When you test if there is a significant difference in the proportions of participants reporting a reduction of symptoms between the experimental and placebo groups. Use α = 0.05. What should the researcher’s conclusion be for a 5% significance level? Reject H0because 2.64 ≥ 1.960. We have statistically significant evidence at α = 0.05 to show that there is a difference in the proportions of patients reporting a reduction in symptoms. We reject H0 at the 5% level because 2.64 is greater than 1.96. We do have statistically…
In a 2005 study 2205 adolescents aged 12 - 19 years old were give a treadmill test to check their cardiovascular health. 750 of the subjects were determined to have poor cardiovascular fitness. The researchers want to claim that more than 30% of adolescents have poor cardiovascular health (with a 5% level of significance). The research hypothesis is Ha:p>0.30. Find the test statistic, p-value, and state your conclusion.
ester Hollar is vice president for human resources for a large manufacturing company. In recent years, he has noticed an increase in absenteeism that he thinks is related to the general health of the employees. Four years ago, in an attempt to improve the situation, he began a fitness program in which employees exercise during their lunch hour. To evaluate the program, he selected a random sample of eight participants and found the number of days each was absent in the six months before the exercise program began and in the six months following the exercise program. Below are the results. Employee Before After 1 6 5 2 6 2 3 7 1 4 7 3 5 4 3 6 3 6 7 5 3 8 6 7 At the 0.05 significance level, can he conclude that the number of absences has declined? Estimate the p-value. State the decision rule for 0.05 significance level. (Round your answer to 3 decimal places.) Compute the test statistic. (Round your answer to 3 decimal places.)
A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 100 participants who receive the experimental medication, 38 report a reduction of symptoms as compared to 21 participants of 100 assigned to placebo. When you test if there is a significant difference in the proportions of participants reporting a reduction of symptoms between the experimental and placebo groups. Use α = 0.05. What should the researcher’s conclusion be for a 5% significance level? Reject H0because 2.64 ≥ 1.960. We have statistically significant evidence at α = 0.05 to show that there is a difference in the proportions of patients reporting a reduction in symptoms. We reject H0 at the 5% level because 2.64 is greater than 1.96. We do have statistically…
You are concerned that nausea may be a side effect of Tamiflu, but you cannot just give Tamiflu to patients with the flu and say that nausea is a side effect if people become nauseous. This is because nausea is common for people who have the flu.Past studies state that about 33% of people who get the flu experience nausea. You collected data on 2248 patients who were taking Tamiflu to relieve symtoms of the flu, and found that 810 experienced nausea. You decide to carry out a simulation to test the claim that the percentage of people who take Tamiflu for the relief of flu symtoms and experience nausea is greater than 33%.a) Identify the null and alternative hypotheses.H0H0: ? p = p ≠ p < p > p ≤ p ≥ μ = μ ≠ μ < μ > μ ≤ μ ≥ H1H1: ? p = p ≠ p < p > p ≤ p ≥ μ = μ ≠ μ < μ > μ ≤ μ ≥
A clinical trial is run to assess the effects of different forms of regular exercise on HDL levels in persons between the ages of 19 and 29. Participants in the study are randomly assigned to one of three exercise groups—weight training, aerobic exercise, or stretching/yoga—and instructed to follow the program for 8 weeks. Their HDL levels are measured after 9 weeks and are summarized below. Exercise Group N Mean Std Dev Weight Training 20 49.7 10.2 Aerobic Exercise 20 43.1 11.1 Stretching/Yoga 20 57.0 12.5 Complete the following ANOVA table. Source of Error Sums of Squares df Mean Squares F Between Within 6157.32 Total 1.Write the hypotheses to be tested. 2. Write the decision rule. Please find the F for the closest df 3. What is the conclusion?
A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 100 participants who receive the experimental medication, 38 report a reduction of symptoms as compared to 21 participants of 100 assigned to placebo. When you test if there is a significant difference in the proportions of participants reporting a reduction of symptoms between the experimental and placebo groups. Use α = 0.05. What should the researcher’s conclusion be for a 5% significance level? Reject H0because 2.64 ≥ 1.960. We have statistically significant evidence at α = 0.05 to show that there is a difference in the proportions of patients reporting a reduction in symptoms. We reject H0 at the 5% level because 2.64 is greater than 1.96. We do have statistically…
Most cases of cervical cancer are linked to a few strains of the human papilloma virus (HPV). The pharmaceutical company Merck developed a vaccine (Gardisil) against these HPV strains. Worldwide clinical trials followed young women after vaccination or administration of placebo for two to four years for signs of HPV-caused cervical cancer. Based on a sample of 100 women in the Gardisil group, 24 % developed cervical cancer, and based on a sample of 100 women in the placebo group, 34 % developed cervical cancer. Test the claim that the proportion of women who developed cervical cancer in the Gardisil group is less than the proportion of women who developed cervical cancer in the placebo group at a = 0.10. Round your answers to three decimal places, and round any interim calculations to four decimal places. Fill in the hypotheses below where p₁ denotes the proportion of women who developed cervical cancer in the Gardisil group and P2 denotes the proportion of women who developed cervical…
A researcher conducts a between-subjects study to determine whether low levels of the neurochemical serotonin leads to an increase in aggression. One sample of rats serves as a control group and receives a placebo that does not affect normal levels of serotonin. A second sample of rats receives a drug that lowers brain levels of serotonin. Using an alpha level of a = .05, the researcher then tests the animals by recording the number of aggressive responses each of the rats display. The data are as follows: a.) Step 1: State the Hypotheses Ho: H₁: Control n = 10 M = 14 SS=180.5 b.) Step 2: Determine the critical region and draw it on the distribution above: df = > *critical SM₁-M₂ Low Serotonin n = 15 M = 19 SS = 130.0 c.) Step 3: Calculate the test statistic using the provided sample data: tobs d.) Step 4: Make a decision. Circle one: Reject Null (Ho) or Fail to Reject Null (Ho) e.) State your conclusions about the research scenario in sentence form: d= f.) What is the estimated effect…

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