Vitamin D is important for maintaining strong bones by helping the body absorb calcium from food and sup-plements. The recommended amount of vitamin D is 400 IU (international units) per day. Many people take vitamin D supplements, often at levels greatly exceeding the recommended daily amount. What is the effect of taking too much vitamin D? Researchers investigated this in a double-blind randomized clinical trial. Subjects were divided into three groups. One, consisting of 109 subjects, took 400 IU per day for three years. second group, consisting of 100 subjects, took 4,000 IU per day for three years. A third group, consisting of 102 subjects, took 10,000 IU per day for three years. The total volumetric bone mass density of the tibia (the large bone located in the lower front portion of the leg, sometimes referred to as the shinbone) was measured in order to assess the effect of the different dosages of Vitamin D.11 The degrees of freedom for the ANOVA F statistic comparing the mean volumetric bone masses are
Vitamin D is important for maintaining strong bones by helping the body absorb calcium from food and sup-plements. The recommended amount of vitamin D is 400 IU (international units) per day. Many people take vitamin D supplements, often at levels greatly exceeding the recommended daily amount. What is the effect of taking too much vitamin D? Researchers investigated this in a double-blind randomized clinical trial. Subjects were divided into three groups. One, consisting of 109 subjects, took 400 IU per day for three years. second group, consisting of 100 subjects, took 4,000 IU per day for three years. A third group, consisting of 102 subjects, took 10,000 IU per day for three years.
The total volumetric bone mass density of the tibia (the large bone located in the lower front portion of the leg, sometimes referred to as the shinbone) was measured in order to assess the effect of the different dosages of Vitamin D.11
The degrees of freedom for the ANOVA F statistic comparing the
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