3.16 A randomized clinical trial compared aspirin to placebo for the prevention of heart attacks (MIs) and strokes. Out of a total of 1,000 subjects on aspirin, there were 80 heart attacks and 65 strokes; out of a total of 2,000 subjects on placebo, there were 240 heart attacks and 165 strokes. Is there a significant benefit for aspirin therapy for heart attacks and strokes? What is the RR for aspirin use for each of these two outcomes? (Careful here, you are given the total number of subjects in each group and the number of complications.)
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- What is an experiment?AD (Alzheimer's disease) causes progressive cognitive impairment. A diagnostic blood test for AD was proposed. An evaluation of the blood text involved fifty known AD patients and forty control who did not have AD. Of those who had AD, forty eight tested positive on the blood test and two tested negative. Of those without AD, three tested positive on the blood test and thirty seven tested negative. d. With a serious disease, it is important that a very high proportion of those who have the disease be detected by the test? Was this the case here? What the name for the proportion is of cases that are detected by a test?One study of cell phones and the risk of brain cancer looked at a group of 469 people who have brain cancer. The investigators then asked about the use of cell phones. Result: “Our data suggest that the use of hand- held cellular phones is not associated with risk of brain cancer. B . Based on this study, can you determine that cellular use does not CAUSE brain cancer? Why or why not?
- In a study of 301 Hispanic women living in San Antonia, Texas, one variable of interest was the percentage of subjects with impaired fasting glucose (IFG). IFG refers to a metabolic stage intermediate between normal glucose homeostasis and diabetes. In the study, 24 women were classified in the IFG stage. The article cites population estimates for IFG among Hispanic women in Texas as 6.3%. Is there sufficient evidence to indicate the population of Hispanic women in San Antonio has a prevalence of IFG higher than 6.3%? Use 95% confidence level and the p -value method to form your conclusion. Answer the problem in a complete sentence.In a study of 301 Hispanic women living in San Antonia, Texas, one variable of interest was the percentage of subjects with impaired fasting glucose (IFG). IFG refers to a metabolic stage intermediate between normal glucose homeostasis and diabetes. In the study, 24 women were classified in the IFG stage. The article cites population estimates for IFG among Hispanic women in Texas as 6.3%. Is there sufficient evidence to indicate the population of Hispanic women in San Antonio has a prevalence of IFG higher than 6.3%? Use 95% confidence level and the p -value method to form your conclusion. The computed z score was 1.193. Find the p-value.In a study of 301 Hispanic women living in San Antonia, Texas, one variable of interest was the percentage of subjects with impaired fasting glucose (IFG). IFG refers to a metabolic stage intermediate between normal glucose homeostasis and diabetes. In the study, 24 women were classified in the IFG stage. The article cites population estimates for IFG among Hispanic women in Texas as 6.3%. Is there sufficient evidence to indicate the population of Hispanic women in San Antonio has a prevalence of IFG higher than 6.3%? Use 95% confidence level and the p -value method to form your conclusion. Choose the correct null and alternative hypothesis.
- As men age, their testosterone levels gradually decrease. This may cause a reduction in energy, an increase in fat, and other undesirable changes. Do testosterone supplements reverse some of these effects? A study in the Netherlands assigned 237 men aged 60 to 80 with low or low-normal testosterone levels to either a testosterone supplement or a placebo. Why is it necessary to include a control group in this experiment? Every experiment needs a control group in order to make proper comparisons between treatments. A control group is necessary to balance the effects of other variables among the treatment groups. A control group is necessary so any differences in the effects of the treatments can be distinguished from chance differences between the groups. A control group helps avoid confounding and reduces variability in the response variable. A control group is used to provide a baseline for comparing the effects of other treatments.An experiment was conducted for better understanding of the effectiveness of a particular type of drug for reducing bad cholesterol (LDL) level. The purpose of the experiment was to determine whether different dosages used have significant different outcomes in average LDL reduction. Twenty subjects with LDL at around 250 to 300 mg/dL had participated in the study and were randomly divided into four groups. Each group was given a specific level of dosage of the drug each day for one month, with a control group that only provided with placebo. The reduction in LDL was recorded and showed in the following table. Positive number indicates reduction and negative numbers indicates increasing in DLD. Use statistical software to analyze the data and answer the following question. Control Light Dosage Level Medium Dosage Level Heavy Dosage Level 7 25 73 81 -3 17 60 71 6 22 55 79 5 21 41 60 15 12 36 85 Perform a One-way…Most cases of cervical cancer are linked to a few strains of the human papilloma virus (HPV). The pharmaceutical company Merck developed a vaccine (Gardisil) against these HPV strains. Worldwide clinical trials followed young women after vaccination or administration of placebo for two to four years for signs of HPV-caused cervical cancer. Based on a sample of 100 women in the Gardisil group, 26% developed cervical cancer, and based on a sample of 100 women in the placebo group, 32% developed cervical cancer. Test the claim that the proportion of women who developed cervical cancer in the Gardisil group is less than the proportion of women who developed cervical cancer in the placebo group at a = 0.05. Round your answers to three decimal places, and round any interim calculations to four decimal places. Fill in the hypotheses below where p₁ denotes the proportion of women who developed cervical cancer in the Gardisil group and p2 denotes the proportion of women who developed cervical…
- Most cases of cervical cancer are linked to a few strains of the human papilloma virus (HPV). The pharmaceutical company Merck developed a vaccine (Gardisil) against these HPV strains. Worldwide clinical trials followed young women after vaccination or administration of placebo for two to four years for signs of HPV-caused cervical cancer. Based on a sample of 100 women in the Gardisil group, 24 % developed cervical cancer, and based on a sample of 100 women in the placebo group, 34 % developed cervical cancer. Test the claim that the proportion of women who developed cervical cancer in the Gardisil group is less than the proportion of women who developed cervical cancer in the placebo group at a = 0.10. Round your answers to three decimal places, and round any interim calculations to four decimal places. Fill in the hypotheses below where p₁ denotes the proportion of women who developed cervical cancer in the Gardisil group and p2 denotes the proportion of women who developed cervical…Most cases of cervical cancer are linked to a few strains of the human papilloma virus (HPV). The pharmaceutical company Merck developed a vaccine (Gardisil) against these HPV strains. Worldwide clinical trials followed young women after vaccination or administration of placebo for two to four years for signs of HPV-caused cervical cancer. Based on a sample of 100 women in the Gardisil group, 24 % developed cervical cancer, and based on a sample of 100 women in the placebo group, 34 % developed cervical cancer. Test the claim that the proportion of women who developed cervical cancer in the Gardisil group is less than the proportion of women who developed cervical cancer in the placebo group at a = 0.10. Round your answers to three decimal places, and round any interim calculations to four decimal places. Fill in the hypotheses below where p₁ denotes the proportion of women who developed cervical cancer in the Gardisil group and P2 denotes the proportion of women who developed cervical…AD (Alzheimer's disease) causes progressive cognitive impairment. A diagnostic blood test for AD was proposed. An evaluation of the blood text involved fifty known AD patients and forty control who did not have AD. Of those who had AD, forty eight tested positive on the blood test and two tested negative. Of those without AD, three tested positive on the blood test and thirty seven tested negative. e. With a serious disease, it is important that a very high proportion of those who does not have the disease be detected by the test? Was this the case here? What is the name for the proportion of cases that are detected by a test?