Subjects with pre-existing cardiovascular symptoms who were receiving subitramine, an appetite suppressant, were found to be at increased risk of cardiovascular events while taking the drug. The study included 9645 overweight or obese subjects with preexisting cardiovascular disease and/ or type 2 diabetes. The subjects were randomly assigned to subitramine (4798 subjects) or a placebo (4847 subjects) in a double-blind fashion. The primary outcome measured was the occurrence of any of the following events: nonfatal myocardial infarction or stroke, resuscitation after cardiac arrest, or cardiovascular death. The primary outcome was observed in 552 subjects in the subitramine group and 491 subjects in the placebo group. Do the data give good reason to think that there is a difference between the proportions of treatment and placebo subjects who experienced the primary outcome? (a) State hypotheses, find the test statistic and use either software or Table A for the P-value. Give both the test statistic and the P-value to three decimal places. Test statistic z = 2.167
Subjects with pre‑existing cardiovascular symptoms who were receiving subitramine, an appetite suppressant, were found to be at increased risk of cardiovascular
Do the data give good reason to think that there is a difference between the proportions of treatment and placebo subjects who experienced the primary outcome?
(a) State hypotheses, find the test statistic and use either software or Table A for the ? Give both the test statistic and the ?-value to three decimal places.
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