In randomized, double-blind clinical trials of a new vaccine, children were randomly divided into two groups. Subjects in group 1 received the newvaccine while subjects in group 2 received a control vaccine. After the second dose, 125 of 746 subjects in the experimental group (group 1)experienced fever as a side effect. After the second dose, 82 of 627 of the subjects in the control group (group 2) experienced fever as a side effect.Does the evidence suggest that a higher proportion of subjects in group 1 experienced fever as a side effect than subjects in group 2 at the x = 0.01 levelof significance?IIIIน IG เC เด อ บ เบา เy เเ เ1.91 (Round to two decimal places as needed.)Determine the P-value for this hypothesis test.(Round to three decimal places as needed.)

The following information has been provided Sample size n1=746 Sample size n2=627 Favourable cases…

Answered: In randomized, double-blind clinical…

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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A pharmaceutical company proposed a vaccine that would combat paralytic polio. Two independent random samples were collected from the population. One random sample of 201,229 was given the placebo, and among them 100,910 contracted paralytic polio. The other random sample of 200,745 was given the vaccine, and among them 50,033 people ended up contracting paralytic polio. Let the true proportion of cases of paralytic polio given placebo be p1p1 and the true proportion of cases of paralytic polio given vaccine be p2. Calculate the upper bound of a 95% confidence interval for p1−p2. Round your answer to three decimal places.
A large clinical trial of the effect of diet on breast cancer assigned women at random to either a normal diet or a low-fat diet. To check that the random assignment did produce comparable groups, we can compare the two groups at the start of the study. Asked if there is a family history of breast cancer: 1276 of the 5964 women in the low-fat group and 1507 of the 7726 women in the control group said "Yes." If the random assignment worked well, there should not be a significant difference in the proportions with a family history of breast cancer. How significant is the observed difference? State: Is there evidence of a difference in the proportion of women with a family history of breast cancer between the treatment and control groups? Plan: Let pi be the proportion for the treatment group, and Pz the proportion for the control group. State the hypotheses for your test. Ha:Pi + P2 Solve: Give the value of the test statistic. Use the calculator. Select an answer ♥ Ho:pi = p2 What is the…
In randomized, double-blind clinical trials of a new vaccine, children were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 125 of 746 subjects in the experimental group (group 1) experienced fever as a side effect. After the second dose, 82 of 627 of the subjects in the control group (group 2) experienced fever as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced fever as a side effect than subjects in group 2 at the a= 0.01 level of significance? Find the test statistic for this hypothesis test. (Round to two decimal places as needed.)
A researcher is creating a new treatment protocol for Myelodysplastic Syndrome (MDS), a form of preleukemia. Following the old treatment protocol, 28% of patients with MDS will develop leukemia within 5 years of MDS diagnosis. He believes his new treatment protocol will lead to fewer MDS patients developing leukemia. He takes a random sample of 100 individuals on his new treatment protocol. Of these 100 individuals, 20 develop leukemia within 5 years of MDS diagnosis. In questions 8-9, create a 98% confidence interval for the true proportion of all MDS patients on this new treatment who will develop leukemia within 5 years of MDS diagnosis. What is the confidence interval? Do not round your answer. What is the interpretation of your confidence interval?
ester Hollar is vice president for human resources for a large manufacturing company. In recent years, he has noticed an increase in absenteeism that he thinks is related to the general health of the employees. Four years ago, in an attempt to improve the situation, he began a fitness program in which employees exercise during their lunch hour. To evaluate the program, he selected a random sample of eight participants and found the number of days each was absent in the six months before the exercise program began and in the six months following the exercise program. Below are the results. Employee Before After 1 6 5 2 6 2 3 7 1 4 7 3 5 4 3 6 3 6 7 5 3 8 6 7 At the 0.05 significance level, can he conclude that the number of absences has declined? Estimate the p-value. State the decision rule for 0.05 significance level. (Round your answer to 3 decimal places.) Compute the test statistic. (Round your answer to 3 decimal places.)
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In the largest clinical trial ever conducted, 401,974 children were randomly assigned to two groups. The treatment group consisted of 201,229 children given the Salk vaccine for polio, and the other 200,745 children were given a placebo. Among those in the treatment group, 33 developed polio, and among those in the placebo group, 115 developed polio. If we want to use the methods for testing a claim about two population proportions to test the claim that the rate of polio is less for children given the Salk vaccine, are the requirements for a hypothesis test satisfied? Explain. Choose the correct answer below. ……… O A. The requirements are satisifed; the samples are simple random samples that are independent, and for each of the two groups, the sample size is at least 1000. O B. The requirements are satisfied; the samples are simple random samples that are independent, and for each of the two groups, the number of successes is at least 5 and the number of failures is at least 5. O C.…
In the largest clinical trial ever conducted, 401,974 children were randomly assigned to two groups. The treatment group consisted of 201,229 children given the Salk vaccine for polio, and the other 200,745 children were given a placebo. Among those in the treatment group, 33 developed polio, and among those in the placebo group, 115 developed polio. If we want to use the methods for testing a claim about two population proportions to test the claim that the rate of polio is less for children given the Salk vaccine, are the requirements for a hypothesis test satisfied? Explain. A The requirements are not satisfied; the samples are not simple random samples that are independent. B. The requirements are satisfied; the samples are simple random samples that are independent, and for each of the two groups, the number of successes is at least 5 and the number of failures is at least 5. C. The requirements are satisifed; the samples are simple random samples…
In randomized, double-blind clinical trials of a new vaccine, monkeys were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 117 of 750 subjects in the experimental group (group 1) experienced drowsiness as a side effect. After the second dose, 74 of 631 of the subjects in the control group (group 2) experienced drowsiness as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the a = 0.05 level of significance? Determine the P-value for this hypothesis test. (Round to three decimal places as needed.) Interpret the P-value. If the population proportions are one would expect a sample difference proportion the one observed in about out of 1000 repetitions of this experiment. (Round to the nearest integer as needed.) State the conclusion for this hypothesis test. A. Reject Ho.…
In randomized, double-blind clinical trials of a new vaccine, rats were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 110 of 703 subjects in the experimental group (group 1) experienced fever as a side effect. After the second dose, 67 of 584 of the subjects in the control group (group 2) experienced fever as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced fever as a side effect than subjects in group 2 at the a = 0.10 level of significance? Verify the model requirements. Select all that apply. A. The samples are independent. В. np1 (1-P1 2 10 and n p2(1-P2 2 10 C. The sample size is less than 5% of the population size for each sample. D. The sample size is more than 5% of the population size for each sample. E. The data come from a population that is normally distributed. F. The samples are dependent. Determine the null and…
A researcher is creating a new treatment protocol for Myelodysplastic Syndrome (MDS), a form of preleukemia. Following the old treatment protocol, 28% of patients with MDS will develop leukemia within 5 years of MDS diagnosis. He believes his new treatment protocol will lead to fewer MDS patients developing leukemia. He takes a random sample of 100 individuals on his new treatment protocol. Of these 100 individuals, 20 develop leukemia within 5 years of MDS diagnosis. Conduct a hypothesis test at the 10% level to test this claim that his new treatment protocol will lead to fewer MDS patients developing leukemia. What is the appropriate conclusion/interpretation for this hypothesis test? Write a few sentences.
In randomized, double-blind clinical trials of a new vaccine, children were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 123 of 460 subjects in the experimental group (group 1) experienced drowsiness as a side effect. After the second dose, 24 of 106 of the subjects in the control group (group 2) experienced drowsiness as a side effect. Does the evidence suggest that a different proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the a = 0.01 level of significance? Determine the null and alternative hypotheses. Choose the correct answer below. A. Ho: P1 =0 versus Ho: P, #0 B. Ho: P =P2 versus H,: P, P2 The test statistic zo is (Round to two decimal places as needed.)

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