In the largest clinical trial ever conducted, 401,974 children were randomly assigned to two groups. The treatment group consisted of​ 201,229 children given the Salk vaccine for​ polio, and the other​ 200,745 children were given a placebo. Among those in the treatment​ group, 33 developed​ polio, and among those in the placebo​ group, 115 developed polio. If we want to use the methods for testing a claim about two population proportions to test the claim that the rate of polio is less for children given the Salk​ vaccine, are the requirements for a hypothesis test​ satisfied? Explain.   A The requirements are not​ satisfied; the samples are not simple random samples that are independent.   B. The requirements are​ satisfied; the samples are simple random samples that are​ independent, and for each of the two​ groups, the number of successes is at least 5 and the number of failures is at least 5.   C. The requirements are​ satisifed; the samples are simple random samples that are​ independent, and for each of the two​ groups, the sample size is at least 1000.   D. The requirements are not​ satisfied; the difference between the rates of those that developed polio in the two groups is not statistically significant.

MATLAB: An Introduction with Applications
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Author:Amos Gilat
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Chapter1: Starting With Matlab
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In the largest clinical trial ever conducted, 401,974 children were randomly assigned to two groups. The treatment group consisted of​ 201,229 children given the Salk vaccine for​ polio, and the other​ 200,745 children were given a placebo. Among those in the treatment​ group, 33 developed​ polio, and among those in the placebo​ group, 115 developed polio. If we want to use the methods for testing a claim about two population proportions to test the claim that the rate of polio is less for children given the Salk​ vaccine, are the requirements for a hypothesis test​ satisfied? Explain.
 
A
The requirements are not​ satisfied; the samples are not simple random samples that are independent.
 
B.
The requirements are​ satisfied; the samples are simple random samples that are​ independent, and for each of the two​ groups, the number of successes is at least 5 and the number of failures is at least 5.
 
C.
The requirements are​ satisifed; the samples are simple random samples that are​ independent, and for each of the two​ groups, the sample size is at least 1000.
 
D.
The requirements are not​ satisfied; the difference between the rates of those that developed polio in the two groups is not statistically significant.
 
 
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