In randomized, double-blind clinical trials of a new vaccine, rats were randomly divided into two groups. Subjects in group 1 received the new vaccinewhile subjects in group 2 received a control vaccine. After the second dose, 110 of 367 subjects in the experimental group (group 1) experienceddrowsiness as a side effect. After the second dose, 169 of 649 of the subjects in the control group (group 2) experienced drowsiness as a side effect.Does the evidence suggest thata higher proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the0.01 level of significance?P2Find the test statistic for this hypothesis test.(Round to two decimal places as needed.)Enter your answer in the answer box and then click Check AnswerpartsremainingCheck AnswerClear All11:54 AM11/17/2019DELLPrtScrF5F3F10InsertscF12F2F11F1F4F6F7F9F8$&+Вс145QEPHKAFVBIAltAltCtrlHomeInspiron 113000 SeriesBB1xUSB J.O PortWAudio Pro00I#mX

There are 110 of 367 subjects in the experimental group1 experienced drowsiness as a side effect and…

Answered: In randomized, double-blind clinical…

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 100 participants who receive the experimental medication, 38 report a reduction of symptoms as compared to 21 participants of 100 assigned to placebo. When you test if there is a significant difference in the proportions of participants reporting a reduction of symptoms between the experimental and placebo groups. Use α = 0.05. What should the researcher’s conclusion be for a 5% significance level? Reject H0because 2.64 ≥ 1.960. We have statistically significant evidence at α = 0.05 to show that there is a difference in the proportions of patients reporting a reduction in symptoms. We reject H0 at the 5% level because 2.64 is greater than 1.96. We do have statistically…
A large clinical trial of the effect of diet on breast cancer assigned women at random to either a normal diet or a low-fat diet. To check that the random assignment did produce comparable groups, we can compare the two groups at the start of the study. Asked if there is a family history of breast cancer: 1276 of the 5964 women in the low-fat group and 1507 of the 7726 women in the control group said "Yes." If the random assignment worked well, there should not be a significant difference in the proportions with a family history of breast cancer. How significant is the observed difference? State: Is there evidence of a difference in the proportion of women with a family history of breast cancer between the treatment and control groups? Plan: Let pi be the proportion for the treatment group, and Pz the proportion for the control group. State the hypotheses for your test. Ha:Pi + P2 Solve: Give the value of the test statistic. Use the calculator. Select an answer ♥ Ho:pi = p2 What is the…
In randomized, double-blind clinical trials of a new vaccine, children were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 125 of 746 subjects in the experimental group (group 1) experienced fever as a side effect. After the second dose, 82 of 627 of the subjects in the control group (group 2) experienced fever as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced fever as a side effect than subjects in group 2 at the a= 0.01 level of significance? Find the test statistic for this hypothesis test. (Round to two decimal places as needed.)
A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 100 participants who receive the experimental medication, 38 report a reduction of symptoms as compared to 21 participants of 100 assigned to placebo. When you test if there is a significant difference in the proportions of participants reporting a reduction of symptoms between the experimental and placebo groups. Use α = 0.05. What should the researcher’s conclusion be for a 5% significance level? Reject H0because 2.64 ≥ 1.960. We have statistically significant evidence at α = 0.05 to show that there is a difference in the proportions of patients reporting a reduction in symptoms. We reject H0 at the 5% level because 2.64 is greater than 1.96. We do have statistically…
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ester Hollar is vice president for human resources for a large manufacturing company. In recent years, he has noticed an increase in absenteeism that he thinks is related to the general health of the employees. Four years ago, in an attempt to improve the situation, he began a fitness program in which employees exercise during their lunch hour. To evaluate the program, he selected a random sample of eight participants and found the number of days each was absent in the six months before the exercise program began and in the six months following the exercise program. Below are the results. Employee Before After 1 6 5 2 6 2 3 7 1 4 7 3 5 4 3 6 3 6 7 5 3 8 6 7 At the 0.05 significance level, can he conclude that the number of absences has declined? Estimate the p-value. State the decision rule for 0.05 significance level. (Round your answer to 3 decimal places.) Compute the test statistic. (Round your answer to 3 decimal places.)
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The Salk vaccine against polio was tested in 1954 in a carefully designed field experiment. Approximately, 400,000 children took part in this experiment. Using a randomization procedure, the children were randomly divided into 2 groups of equal size, a treatment group, and a control group. The vaccine was given only to the children in the treatment group; the control group children received placebo injections. The children did not know which of the two groups they had been placed into. The diagnosticians also lacked this information. 57 children in the treatment group went on to contract polio, while 142 children in the control group contracted the illness. How likely would such a difference in outcomes be when the assignment to the treatment or control group had absolutely no effect on the outcomes?
In randomized, double-blind clinical trials of a new vaccine, monkeys were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 117 of 750 subjects in the experimental group (group 1) experienced drowsiness as a side effect. After the second dose, 74 of 631 of the subjects in the control group (group 2) experienced drowsiness as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the a = 0.05 level of significance? Determine the P-value for this hypothesis test. (Round to three decimal places as needed.) Interpret the P-value. If the population proportions are one would expect a sample difference proportion the one observed in about out of 1000 repetitions of this experiment. (Round to the nearest integer as needed.) State the conclusion for this hypothesis test. A. Reject Ho.…
A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 100 participants who receive the experimental medication, 38 report a reduction of symptoms as compared to 21 participants of 100 assigned to placebo. When you test if there is a significant difference in the proportions of participants reporting a reduction of symptoms between the experimental and placebo groups. Use α = 0.05. What should the researcher’s conclusion be for a 5% significance level? Reject H0because 2.64 ≥ 1.960. We have statistically significant evidence at α = 0.05 to show that there is a difference in the proportions of patients reporting a reduction in symptoms. We reject H0 at the 5% level because 2.64 is greater than 1.96. We do have statistically…
A researcher is creating a new treatment protocol for Myelodysplastic Syndrome (MDS), a form of preleukemia. Following the old treatment protocol, 28% of patients with MDS will develop leukemia within 5 years of MDS diagnosis. He believes his new treatment protocol will lead to fewer MDS patients developing leukemia. He takes a random sample of 100 individuals on his new treatment protocol. Of these 100 individuals, 20 develop leukemia within 5 years of MDS diagnosis. Conduct a hypothesis test at the 10% level to test this claim that his new treatment protocol will lead to fewer MDS patients developing leukemia. What is the appropriate conclusion/interpretation for this hypothesis test? Write a few sentences.

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