Match the primary sequence to its characteristics/function/fate 1. mostly hydrophobic, interacts with SRP, cut off v N-signal v signal-anchor 2. hydrophobic, interacts with SRP and translocon, becomes transmembrane helix v stop-anchor 3. found at carboxyl terminus of ER resident proteins, interaction with its receptor directs retrieval from Golgi v nuclear localization sequence 4. hydrophobic, interacts with translocon, becomes transmembrane helix v KDEL 5. basic, interacts with importin-alpha

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Match the primary sequence to its characteristics/function/fate:

1. **N-signal**  
   - Mostly hydrophobic, interacts with SRP, cut off

2. **Signal-anchor**  
   - Hydrophobic, interacts with SRP and translocon, becomes transmembrane helix

3. **Stop-anchor**  
   - Hydrophobic, interacts with translocon, becomes transmembrane helix

4. **Nuclear localization sequence**  
   - Basic, interacts with importin-alpha

5. **KDEL**  
   - Found at carboxyl terminus of ER resident proteins, interaction with its receptor directs retrieval from Golgi
Transcribed Image Text:Match the primary sequence to its characteristics/function/fate: 1. **N-signal** - Mostly hydrophobic, interacts with SRP, cut off 2. **Signal-anchor** - Hydrophobic, interacts with SRP and translocon, becomes transmembrane helix 3. **Stop-anchor** - Hydrophobic, interacts with translocon, becomes transmembrane helix 4. **Nuclear localization sequence** - Basic, interacts with importin-alpha 5. **KDEL** - Found at carboxyl terminus of ER resident proteins, interaction with its receptor directs retrieval from Golgi
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