A researcher studying late-onset Alzheimer's disease is interested in a gene, called ApoE, that codes for a neuronal protein with many different variants. The boxes in this diagram represent the ApoE coding sequence. The ATG start codon is located in exon 1. The lines between exons represent introns. Which of the following alternative mRNA splicing events would likely result in the production of a functional protein variant? Exon 1 Exon 2 Exon 3 Exon 4 5' UTR 3' UTR 3' UTR Removal of Exon 4 only Removal of any one Exon Removal of either Exon 3 or Exon 4 but not both Removal of Exon 3 only Removal of Exon 1 only

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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A researcher studying late-onset Alzheimer's disease is interested in a gene, called ApoE, that codes for a neuronal protein with many different variants. The boxes in this
diagram represent the ApoE coding sequence. The ATG start codon is located in exon 1. The lines between exons represent introns. Which of the following alternative mRNA
splicing events would likely result in the production of a functional protein variant?
Exon 1
Exon 2
Exon 3
Exon 4
5' UTR
3' UTR
3' UTR
Removal of Exon 4 only
Removal of any one Exon
Removal of either Exon 3 or Exon 4 but not both
Removal of Exon 3 only
Removal of Exon 1 only
Transcribed Image Text:A researcher studying late-onset Alzheimer's disease is interested in a gene, called ApoE, that codes for a neuronal protein with many different variants. The boxes in this diagram represent the ApoE coding sequence. The ATG start codon is located in exon 1. The lines between exons represent introns. Which of the following alternative mRNA splicing events would likely result in the production of a functional protein variant? Exon 1 Exon 2 Exon 3 Exon 4 5' UTR 3' UTR 3' UTR Removal of Exon 4 only Removal of any one Exon Removal of either Exon 3 or Exon 4 but not both Removal of Exon 3 only Removal of Exon 1 only
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