Interleukin-6 is an important pro-inflammatory cytokine released in response to a variety of infections. Tocilizumab is a monoclonal antibody that blocks the action of IL-6. This drug cannot be given orally. Provide a biochemical explanation for this.
Interleukin-6 is an important pro-inflammatory cytokine released in response to a variety of infections. Tocilizumab is a monoclonal antibody that blocks the action of IL-6. This drug cannot be given orally. Provide a biochemical explanation for this.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Interleukin-6 is an important pro-inflammatory cytokine released in response to a variety of infections. Tocilizumab is a
monoclonal antibody that blocks the action of
IL-6. This drug cannot be given orally. Provide a biochemical explanation for this.
Expert Solution
Step 1
Tocilizumab is Monoclonal antibody which is use against soluble or membrane bound IL 6 and prevent IL 6 from binding and signaling. It is also used to treat hyper inflammatory state and autoimmune diseases.
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