If there are multiple start condo, how can you identify the real start codon? By observing Okazaki fragments By identifying splicing site Using sequence data bases By identifying Kozak sequence Which one is not a part of the transcription unit? RNA primase Promoter RNA coding sequence Terminator

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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  1. If there are multiple start condo, how can you identify the real start codon?
  2. By observing Okazaki fragments
  3. By identifying splicing site
  4. Using sequence data bases
  5. By identifying Kozak sequence
  6. Which one is not a part of the transcription unit?
  7. RNA primase
  8. Promoter
  9. RNA coding sequence
  10. Terminator
Expert Solution
Introduction:

Transcription and translation are specialized events that are part of the central dogma i.e. DNA to RNA to Protein.

Answer 1:

Correct Option -By identifying Kozak sequence

The Kozak sequence is a sequence that acts as the initiating sequence in eukaryotic organisms. When there are multiple start codons, this sequence is the one that marks the initiating site for translation. A part of the Kozak sequence is conserved and seen in most mRNAs with minute one or two changes beyond it. It ranges from nucleotide number -6 to +6; if +1 is assigned to adenine of the AUG (METHIONINE) codon. 

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