1.You are investigating a protein that has the amino acid sequenceN ... Ala – Thr - Asn – Trp – Lys - Arg - Gly – Phe – Thr ... Cwithin its primary structure. You found that several of the mutations affecting this proteinproduced shortened protein molecules that terminated within this region. In one of the mutants,the Asn became the terminal (last) amino acid.(a) What DNA single-base changes(s) would cause the protein to terminate at the Asnresidue?(b) What other potential sites do you see in the DNA sequence encoding this protein wheremutation of a single base pair would cause premature termination of translation?> FontParagraphStylesDictateSensitivityThe human gene for B2 lens crystalline has the components listed below. Thenumbers represent nucleotide pairs that make up the particular component. Assume forsimplicity that no alternative splicing is involved and splicing occurs after transcription.5 UTR1st exon1st intronond exon1741195323372nd intron3rd exon3rd intron14312083804th exon4444th intron5th exon995463 UTR715Answer the following questions about the B2 lens crystalline gene, primary transcript, and geneproduct. Questions asking where should be answered with one of the 11 components from the list orwith None. Assume that poly-A tails contain 150 As. (Hint: make a sketch, above or on scratch paper)a. How large is the B2 lens crystalline gene in bp (base pairs)?b. How large is the primary transcript for B2 lens rystalline in bases?c. How large is the mature mRNA for B2 lens crystalline in bases?>d. Where would you find the base pairs encoding the initiation codon?c. Where would you find the base pairs encoding the stop codon?107%FocusPage 4 of 111688 wordsAa

Name: 1.You are investigating a protein that has the amino acid sequenceN .
Uploaded: 2024-03-20T06:42:55.000Z
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Description: 1.You are investigating a protein that has the amino acid sequenceN ... Ala – Thr - Asn – Trp – Lys - Arg - Gly – Phe – Thr ... Cwithin its primary structure. You found that several of the mutations affecting this proteinproduced shortened protein m