How many moles of ATP and GTP will be in use for this polypeptide chain synthesis? What post-translational modifications may be for this protein? Task 2 It is known that ribozymes may be participators of translation pathway. Prove this fact.
Variant 1
Task 1
One single polypeptide chain (120 amino acid residues) is produced for protein A in prokaryotic cell. N-terminal amino acid is alanine in the chain of this protein. How many moles of ATP and GTP will be in use for this polypeptide chain synthesis? What post-translational modifications may be for this protein?
Task 2
It is known that ribozymes may be participators of translation pathway. Prove this fact.
As per the central dogma of molecular biology, the genetic information stored in the DNA is copied onto an mRNA by an DNA dependent RNA polymerase. This process is called transcription. The genetic information, in the form of the genetic code on the mRNA is translated into a polypeptide by ribosomes with the help of tRNA. This process is called translation.
The newly synthesized polypeptide then folds onto itself and undergoes post translational modifications to become attain a three dimensional structure to serve as a functional proteins.
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