synthetic pathwa hway is undeter

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
icon
Concept explainers
Question
I’m having trouble identifying which compound E could produce the pathway
Yeast mutant analysis
Several yeast mutants are isolated in a mutagenic screen for an
important biosynthetic pathway, which makes a compound E that is
required for growth. Although it is known that A, B, C, and D are needed
in the biosynthetic pathway that produces the end product E, their order
in the pathway is undetermined. Each compound is tested for its ability
to support the growth of four different mutants. In the following table, a
plus (+) sign indicates growth and a minus (-) sign indicates no growth.
mutant 1
mutant 2
mutant 3
mutant 4
DEC
8.
MacBook A
1++
Transcribed Image Text:Yeast mutant analysis Several yeast mutants are isolated in a mutagenic screen for an important biosynthetic pathway, which makes a compound E that is required for growth. Although it is known that A, B, C, and D are needed in the biosynthetic pathway that produces the end product E, their order in the pathway is undetermined. Each compound is tested for its ability to support the growth of four different mutants. In the following table, a plus (+) sign indicates growth and a minus (-) sign indicates no growth. mutant 1 mutant 2 mutant 3 mutant 4 DEC 8. MacBook A 1++
As these are yeast cells, you can get complementation between
haploid mutant strains when creating diploid double heterozygotes.
Which of the following crosses successfully complements in order to
generate diploid progeny that could produce compound E in a
functional pathway? Assume the mutations in these mutant lines are
recessive.
mutant 4 x mutant 4
mutant 1 x mutant 4 OR mutant 2 x mutant 4
mutant 1 x mutant 1 OR mutant 4 x mutant 4
O mutant 1 x mutant 1
Transcribed Image Text:As these are yeast cells, you can get complementation between haploid mutant strains when creating diploid double heterozygotes. Which of the following crosses successfully complements in order to generate diploid progeny that could produce compound E in a functional pathway? Assume the mutations in these mutant lines are recessive. mutant 4 x mutant 4 mutant 1 x mutant 4 OR mutant 2 x mutant 4 mutant 1 x mutant 1 OR mutant 4 x mutant 4 O mutant 1 x mutant 1
Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Metabolic pathways
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education