synthetic pathwa hway is undeter

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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I’m having trouble identifying which compound E could produce the pathway
Yeast mutant analysis
Several yeast mutants are isolated in a mutagenic screen for an
important biosynthetic pathway, which makes a compound E that is
required for growth. Although it is known that A, B, C, and D are needed
in the biosynthetic pathway that produces the end product E, their order
in the pathway is undetermined. Each compound is tested for its ability
to support the growth of four different mutants. In the following table, a
plus (+) sign indicates growth and a minus (-) sign indicates no growth.
mutant 1
mutant 2
mutant 3
mutant 4
DEC
8.
MacBook A
1++
Transcribed Image Text:Yeast mutant analysis Several yeast mutants are isolated in a mutagenic screen for an important biosynthetic pathway, which makes a compound E that is required for growth. Although it is known that A, B, C, and D are needed in the biosynthetic pathway that produces the end product E, their order in the pathway is undetermined. Each compound is tested for its ability to support the growth of four different mutants. In the following table, a plus (+) sign indicates growth and a minus (-) sign indicates no growth. mutant 1 mutant 2 mutant 3 mutant 4 DEC 8. MacBook A 1++
As these are yeast cells, you can get complementation between
haploid mutant strains when creating diploid double heterozygotes.
Which of the following crosses successfully complements in order to
generate diploid progeny that could produce compound E in a
functional pathway? Assume the mutations in these mutant lines are
recessive.
mutant 4 x mutant 4
mutant 1 x mutant 4 OR mutant 2 x mutant 4
mutant 1 x mutant 1 OR mutant 4 x mutant 4
O mutant 1 x mutant 1
Transcribed Image Text:As these are yeast cells, you can get complementation between haploid mutant strains when creating diploid double heterozygotes. Which of the following crosses successfully complements in order to generate diploid progeny that could produce compound E in a functional pathway? Assume the mutations in these mutant lines are recessive. mutant 4 x mutant 4 mutant 1 x mutant 4 OR mutant 2 x mutant 4 mutant 1 x mutant 1 OR mutant 4 x mutant 4 O mutant 1 x mutant 1
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