10. The baker's yeast Saccharomyces cerevisiae is able to make uracil from simpler compounds (biosynthesis). A scientist doing research on pyrimidine biosynthesis isolated four mutant strains of yeast that were unable to make their own uracil. These strains are called ura- mutants. To determine if the different strain had mutations in the same gene, or in different genes, she performed complementation tests. She mated all of the strains in all of the possible combinations, and then determined if the hybrids had a ura- phenotype, or if they were normal wild type. The results are given in the table below. A "-" means that when the two strains were mated, their hybrid was still ura-. A "+" means that when the two strain were mated, their hybrid was normal wild type and able to make its own uracil. strain 1 strain 2 strain 3 strain 4 strain 1 strain 2 + strain 3 + strain 4 + + + A. How many different genes are represented by these mutant strains? B. Which mutant strains have mutations in the same gene, and which strains have mutations in genes that are different from all of the others?

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10. The baker's yeast Saccharomyces cerevisiae is able to make uracil from simpler compounds (biosynthesis). A
scientist doing research on pyrimidine biosynthesis isolated four mutant strains of yeast that were unable to make their
own uracil. These strains are called ura- mutants. To determine if the different strain had mutations in the same gene, or
in different genes, she performed complementation tests. She mated all of the strains in all of the possible combinations,
and then determined if the hybrids had a ura- phenotype, or if they were normal wild type. The results are given in the
table below. A "-" means that when the two strains were mated, their hybrid was still ura-. A “+” means that when the
two strain were mated, their hybrid was normal wild type and able to make its own uracil.
strain 1
strain 2
strain 3
strain 4
strain 1
strain 2
+
strain 3
+
strain 4
+
+
+
A. How many different genes are represented by these mutant strains?
B. Which mutant strains have mutations in the same gene, and which strains have mutations in genes that are different
from all of the others?
Transcribed Image Text:10. The baker's yeast Saccharomyces cerevisiae is able to make uracil from simpler compounds (biosynthesis). A scientist doing research on pyrimidine biosynthesis isolated four mutant strains of yeast that were unable to make their own uracil. These strains are called ura- mutants. To determine if the different strain had mutations in the same gene, or in different genes, she performed complementation tests. She mated all of the strains in all of the possible combinations, and then determined if the hybrids had a ura- phenotype, or if they were normal wild type. The results are given in the table below. A "-" means that when the two strains were mated, their hybrid was still ura-. A “+” means that when the two strain were mated, their hybrid was normal wild type and able to make its own uracil. strain 1 strain 2 strain 3 strain 4 strain 1 strain 2 + strain 3 + strain 4 + + + A. How many different genes are represented by these mutant strains? B. Which mutant strains have mutations in the same gene, and which strains have mutations in genes that are different from all of the others?
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