Homework Help is Here – Start Your Trial Now!
Science
Biology
Horizontal sequence :VIRL Vertical sequence:MKF   Scoring rules: g/o = -3, g/e = -1, match or mismatch - from PAM250 substitution matrix below.    SW algorithm.    1. Complete the scoring matrix.    Scoring matrix with PAM250 scores:     V I R L M         K         F           2. Set up, initialize and complete the SW matrix.  3. Retrace, align and score alignment(s).             Use the arrows and circles for the matrix and path(s).                                                                                                                                                                                                                                                                                                                                 V I R L             M           K           F             Align and score all optimal alignments here.

Horizontal sequence :VIRL Vertical sequence:MKF   Scoring rules: g/o = -3, g/e = -1, match or mismatch - from PAM250 substitution matrix below.    SW algorithm.    1. Complete the scoring matrix.    Scoring matrix with PAM250 scores:     V I R L M         K         F           2. Set up, initialize and complete the SW matrix.  3. Retrace, align and score alignment(s).             Use the arrows and circles for the matrix and path(s).                                                                                                                                                                                                                                                                                                                                 V I R L             M           K           F             Align and score all optimal alignments here.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Question

Horizontal sequence :VIRL

Vertical sequence:MKF

 

Scoring rules: g/o = -3, g/e = -1, match or mismatch - from PAM250 substitution matrix below. 

 

  1. SW algorithm. 

 

1. Complete the scoring matrix. 

 

Scoring matrix with PAM250 scores:

 

 

V

I

R

L

M

 

 

 

 

K

 

 

 

 

F

 

 

 

 

 

2. Set up, initialize and complete the SW matrix. 

3. Retrace, align and score alignment(s).            

Use the arrows and circles for the matrix and path(s).                                                                                                                                                                                                                                                                                                                            

 

 

V

I

R

L

 

 

 

 

 

 

M

 

 

 

 

 

K

 

 

 

 

 

F

 

 

 

 

 

 

Align and score all optimal alignments here. 

 

PAM250: Cys 12 Ser T Thr -2 1 P Pro -3 1 :0 A Ala G Gly -2 1 1 2 -3 1 :0 -1:1:5 N Asn -4 1 0:-1 0: 0 D Asp E Glu -5 0:0 :-1 0:1 2 4 -5 -1 0: 0 1 3 4 Gln -5 -1:0 -1 1 : 2 4 Н His R Arg K Lys -3 -1 -1:0 -1 -2 1 1 -4 -1 -2 -3 -1 1 6. -5 -1 -1 -2 1 : 1 : 3: 5 M Met -5 -2 : -1: -2: -1 -3 -2 -3 -2 -1 -2 0: 0 6. Ile -2 -1 0 -2 -1 -3 -2 :-2 -2 : -2 -2: -2 -2 2 L Leu -6 -3 -2:-3 -2 -4 |-3 -4 -3 : -2 -2 : -3 -3 4 2 6. V Val -2 -1 :0 -1:0 -2 -2 -2 -2 -2 -2 -2 2 4 4 F Phe Y Tyr W Trp -4 -3 : -3 : -5 -5 -5 -4 : -6 : -5: -5 -2 : -4 : -5 1 -1 -3: -3 : -5 -3: -5 -2 : -4 : -4: -4 -4: -4 -2 -1: -1: -2 7 10 -8 -2 -5 -6: -6 -7 -4 -7 -7: -5 -3: 2 -3 -4 : -5 -2 -6 17 T P A G D E H. R. K M V F Y W 6:N
Transcribed Image Text:PAM250: Cys 12 Ser T Thr -2 1 P Pro -3 1 :0 A Ala G Gly -2 1 1 2 -3 1 :0 -1:1:5 N Asn -4 1 0:-1 0: 0 D Asp E Glu -5 0:0 :-1 0:1 2 4 -5 -1 0: 0 1 3 4 Gln -5 -1:0 -1 1 : 2 4 Н His R Arg K Lys -3 -1 -1:0 -1 -2 1 1 -4 -1 -2 -3 -1 1 6. -5 -1 -1 -2 1 : 1 : 3: 5 M Met -5 -2 : -1: -2: -1 -3 -2 -3 -2 -1 -2 0: 0 6. Ile -2 -1 0 -2 -1 -3 -2 :-2 -2 : -2 -2: -2 -2 2 L Leu -6 -3 -2:-3 -2 -4 |-3 -4 -3 : -2 -2 : -3 -3 4 2 6. V Val -2 -1 :0 -1:0 -2 -2 -2 -2 -2 -2 -2 2 4 4 F Phe Y Tyr W Trp -4 -3 : -3 : -5 -5 -5 -4 : -6 : -5: -5 -2 : -4 : -5 1 -1 -3: -3 : -5 -3: -5 -2 : -4 : -4: -4 -4: -4 -2 -1: -1: -2 7 10 -8 -2 -5 -6: -6 -7 -4 -7 -7: -5 -3: 2 -3 -4 : -5 -2 -6 17 T P A G D E H. R. K M V F Y W 6:N
Expert Solution
steps

Step by step

Solved in 2 steps with 3 images

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Genomics
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS