GPCR: What would the following mutation mean for the status of the signaling pathway, and the generation of cAMP from ATP? 1) G-protein coupled receptor (GPCR) Loss of Function, in combination with Gain of function of PKA catalytic subunitsa) Pathway ON (final output achieved)b) Pathway OFF (no final output)c) cAMP generatedd) cAMP not generated 2) G-protein coupled receptor (GPCR) Gain of Function, in combination with Loss of function of PKA catalytic subunitsa) Pathway ON (final output achieved)b) Pathway OFF (no final output)c) cAMP generatedd) cAMP not generated
GPCR: What would the following mutation mean for the status of the signaling pathway, and the generation of cAMP from ATP? 1) G-protein coupled receptor (GPCR) Loss of Function, in combination with Gain of function of PKA catalytic subunitsa) Pathway ON (final output achieved)b) Pathway OFF (no final output)c) cAMP generatedd) cAMP not generated 2) G-protein coupled receptor (GPCR) Gain of Function, in combination with Loss of function of PKA catalytic subunitsa) Pathway ON (final output achieved)b) Pathway OFF (no final output)c) cAMP generatedd) cAMP not generated
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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GPCR: What would the following mutation mean for the status of the signaling pathway, and the generation of cAMP from ATP?
1) G-protein coupled receptor (GPCR) Loss of Function, in combination with Gain of function of PKA catalytic subunits
a) Pathway ON (final output achieved)
b) Pathway OFF (no final output)
c) cAMP generated
d) cAMP not generated
2) G-protein coupled receptor (GPCR) Gain of Function, in combination with Loss of function of PKA catalytic subunits
a) Pathway ON (final output achieved)
b) Pathway OFF (no final output)
c) cAMP generated
d) cAMP not generated
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