a) Create a diagram which illustrates the typical signalling mechanism of action of kinase-linked receptors and possible routes of communication (autocrine etc.). Should show thespecific molecules involved, the mechanisms of signal transduction and indicate thedifferent pathways that are activated. It should include a specific example of a receptor,ligand and signalling pathway for each general class. Include as wide a variety of ligandsand modes of action as you can. for a novel pathway.SuperfamilyGive the superfamily to which the receptor belongsAccessionGive the Uniprot accession numberNameGive the molecule nameSpeciesGive the speciesLigandWhat is the ligand, or class of ligands which bind to this receptor?What are the physiological processes involved? Is this autocrine,paracrine or endocrine or some combination of them? What is thepathology of the receptor?KeyphysiologicalprocessinvolvedMechanism of What are the downstream actions of the receptor? Which moleculesactiondoes it interact with, how, and to what effect? How rapidly doe theeffects appear?Key reference Give one key journal reference in Vancouver format that describes themode of action of the receptor

Answered: linked receptors and possible routes of…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Related questions

Question

a) Create a diagram which illustrates the typical signalling mechanism of action of kinase-
linked receptors and possible routes of communication (autocrine etc.). Should show the
specific molecules involved, the mechanisms of signal transduction and indicate the
different pathways that are activated. It should include a specific example of a receptor,
ligand and signalling pathway for each general class. Include as wide a variety of ligands
and modes of action as you can. for a novel pathway.
Superfamily
Give the superfamily to which the receptor belongs
Accession
Give the Uniprot accession number
Name
Give the molecule name
Species
Give the species
Ligand
What is the ligand, or class of ligands which bind to this receptor?
What are the physiological processes involved? Is this autocrine,
paracrine or endocrine or some combination of them? What is the
pathology of the receptor?
Key
physiological
process
involved
Mechanism of What are the downstream actions of the receptor? Which molecules
action
does it interact with, how, and to what effect? How rapidly doe the
effects appear?
Key reference Give one key journal reference in Vancouver format that describes the
mode of action of the receptor

Expert Solution

Step 1

Cell signaling is the process by which signals from one cell are conveyed to other cells known as target cells. Each target cell has a unique receptor to which a ligand or signal binds and exerts its impact.
The process of cell signaling entails the conversion of one event into another. A sensory cell is exposed to an external signal that is transduced to produce a neurological signal, the action potential, in sensory transduction. This action potential can travel via cell membranes to quickly transmit the signal, the action potential, to distant regions of the sensory neuron.
The action potential is then transduced, causing neurotransmitters to be released at the synapse—the space between two neurons.