In expressing therapeutic proteins (check all that apply): Bacteria could be used if you want the protein's disulfide bonds formed before secretion from the bacterial cell. The N-terminal signal sequence and the C chain of insulin must be cleaved off in the rough ER before it's active. Proteolytic protein maturation can be performed by mammalian cells. □ One of the required modifications to preproinsulin, before it's mature, is glycosylation. Both preproinsulin and proinsulin are inactive proteins. U
In expressing therapeutic proteins (check all that apply): Bacteria could be used if you want the protein's disulfide bonds formed before secretion from the bacterial cell. The N-terminal signal sequence and the C chain of insulin must be cleaved off in the rough ER before it's active. Proteolytic protein maturation can be performed by mammalian cells. □ One of the required modifications to preproinsulin, before it's mature, is glycosylation. Both preproinsulin and proinsulin are inactive proteins. U
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter4: Cells
Section: Chapter Questions
Problem 1ITD
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![In expressing therapeutic proteins (check all that apply):
O Bacteria could be used if you want the protein's disulfide bonds formed before secretion from the bacterial cell.
The N-terminal signal sequence and the C chain of insulin must be cleaved off in the rough ER before it's active.
O Proteolytic protein maturation can be performed by mammalian cells.
□ One of the required modifications to preproinsulin, before it's mature, is glycosylation.
Both preproinsulin and proinsulin are inactive proteins.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd925a7d0-2d71-40a6-8b68-0ad6fc3b6bde%2F063c41ed-ead5-420f-a0db-301afd8da4da%2Fo1jrlw6j_processed.png&w=3840&q=75)
Transcribed Image Text:In expressing therapeutic proteins (check all that apply):
O Bacteria could be used if you want the protein's disulfide bonds formed before secretion from the bacterial cell.
The N-terminal signal sequence and the C chain of insulin must be cleaved off in the rough ER before it's active.
O Proteolytic protein maturation can be performed by mammalian cells.
□ One of the required modifications to preproinsulin, before it's mature, is glycosylation.
Both preproinsulin and proinsulin are inactive proteins.
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