You attempt to genera channels in cultured pentobarbital and perfor current at any voltage. WI explain vour findings?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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You attempt to generate an IV plot for GABA
channels
in
cultured
neurons.
You
apply
pentobarbital and perform voltage steps but see no
current at any voltage. Which of the following would
explain your findings?
Concentration of pentobarbital is too low
GABA is not present in your solutions
Cl- concentration is equal on both sides of the
membrane
None of the above
Transcribed Image Text:You attempt to generate an IV plot for GABA channels in cultured neurons. You apply pentobarbital and perform voltage steps but see no current at any voltage. Which of the following would explain your findings? Concentration of pentobarbital is too low GABA is not present in your solutions Cl- concentration is equal on both sides of the membrane None of the above
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