For the case n = 5, the equilibrium constant for this reaction, Keg, is 5-10³ and for n= 6 Keg = 2-105. In terms ofAG°, by how much does a single A:U base pair stabilize such an RNA duplex? %3D
For the case n = 5, the equilibrium constant for this reaction, Keg, is 5-10³ and for n= 6 Keg = 2-105. In terms ofAG°, by how much does a single A:U base pair stabilize such an RNA duplex? %3D
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Question

Transcribed Image Text:3. Short RNA sequences of the form AUn (n is an integer less than, say, 10) are self-
complimentary and dimerize to form RNA duplexes, i.e.,
2 A,U, 1E96 [A,UJz
For the case n= 5, the equilibrium constant for this reaction, Keq, is 5:103 and for n = 6 Keg
= 2-105. In terms of AG°, by how much does a single A:U base pair stabilize such an RNA
duplex?

Transcribed Image Text:4. A molecule has two conformational states that differ by 25 kJ mol-1. What proportion of
molecules are in the most-probable state at 25 °C?
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