What would the following sequence of dodecapeptide M be
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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What would the following sequence of dodecapeptide M be? My best guess would be option C

Transcribed Image Text:After purification of dodecapeptide M, it was sequenced yielding the
following data:
(1) the C-terminal is lle;
(2) the N-terminal is Met;
(3) the following six segments were obtained from various protease
treatments:
Gly-Thr-Arg-Lys-Glu-Ala-Ala-lle
Met
Phe-Pro-Met
Glu-Ala-Ala-lle
Lys
Met-Phe-Pro-Met-Gly-Thr-Arg
What is the sequence of dodecapeptide M?
Met-Phe-Pro-Met-Gly-Thr-Arg-Lys-Glu-Ala-Ala-lle
Met-Gly-Thr-Arg-Lys-Glu-Ala-Ala-Phe-Pro-Met-lle
Met-Phe-Pro-Met-Gly-Thr-Arg-Glu-Ala-Ala-lle-Lys
Met-Lys-Phe-Pro-Met-Gly-Thr-Arg-Glu-Ala-Ala-lle
lle-Ala-Ala-Glu-Lys-Arg-Thr-Gly-Met-Pro-Phe-Met
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