A Phe Cys «N-terminus Cys Met Cys- C-terminus B

Q: (c) Outline how you would investigate whether BCMAP would be an effective inhibitor for the protein…

A: Inhibitors are the molecules that slow down or completely block the protein activity of molecules,…

Q: The determination of the mass of a protein by mass spectrometry often does not allow its unique…

A: Trypsin : It is an enzyme that helps us digestion protein. In the small intestine, trypsin breaks…

Q: Determine the sequence of the decapeptide given the following information below. The decapeptide was…

A: Decapeptide is a peptide that contains 10 amino acids in it. The amino acids present are 3 units of…

Q: Hydrolysis of dodecapeptide P with the enzyme trypsin affords the following fragments: Glu-Ala-Lys,…

A: Trypsin cleaves the dodecapeptide at the carboxyl side of Lys or Arg. Chymotrypsin cleaves the…

Q: Draw the arrow-pushing mechanism for this knowing that histidine amino acid residue acts as a…

A:

Q: A tridecapeptide yields the following fragments when partially hydrolized. Determine the sequence of…

A: A tridecapeptide is an oligopeptide having thirteen amino acid residues.

Q: Briefly describe each of the following possible posttranslational protein modifications.  Give an…

A: The deoxyribonucleic acid (DNA) is the genetic material of the organism that is transcripted to form…

Q: The sequence of a 29 aa long peptide can be determined from the following data: Treatment of the…

A: A peptide is an amino acid chain that is small in length. The amino acids in a peptide are linked…

Q: Purification of a protein of unknown structure has been achieved. The natural protein has a…

A: Proteins are polymers of amino acids and form primary structure. It can form secondary, tertiary and…

Q: In the fungus Neurospora, some mutants were obtained that lacked activity for a certain enzyme. The…

A: Biomolecules are organic compounds found in living organisms. All living organism will have these…

Q: The following peptide that has been acetylated at the C-terminus: CH3C(O)-GEEGH-NH2 Plot the…

A: Titration is a very useful procedure to estimate the concentration of any unknown compound in a…

Q: The following steps were performed using enzyme cleavage of a peptide to determine its amino acid…

A: Sequence of amino acids in a peptide are determined by treating the peptide with different agents…

Q: Cyclic nucleotides (e.g., CGMP, CAMP) frequently make use of the same parts of the ribose ring;…

A: cGMP and cAMP are cyclic nucleotides where a cyclic bond is formed between sugar and phosphate…

Q: calculate the molecular weights of proteins

A: Amino acids are the monomer units of peptides and proteins and they vary from 89 Dalton (Alanine) to…

Q: Consider the following polypeptide sequence: Gly Val Tyr Ile Val Asp His Phe Thr Gly Asn Tyr Ala Leu…

A: Trypsin breaks down proteins in the duodenum into smaller peptides. Other proteases would further…

Q: Consider the hypothetical serine protease in the image, which shows the specificity pockets. The S,…

A: Proteases:  These are enzymes that cleave peptide bonds of an amino acid chain of the protein. In…

Q: Why do we not indicate the side chains of the amino acids that form the peptide bond (see Figure…

A: Peptide bond forms when two amino acids react with each other through their alpha-amino and…

Q: Calculate the pl of the following Peptide

A: At extreme low pH, molecule is fully protonated as the pH increase more than pKa of an ionizable…

Q: An oligopeptide ALVGALGATPTPQMWSHSWRGVSIKS was digested with trypsin.Which method would be most…

A: CHROMATOGRAPHY It is a technique of separation of molecules on the basis of solubility into two…

Q: A polypeptide is digested with trypsin, and the resulting segments are sequenced:…

A: Introduction: A number of enzymes catalyze the breakdown of peptide bonds at a specific site in an…

Q: Can the same pepptide be used in multiple different proteins? yes or no, explain.

A: Proteins are one of the essential biomolecules necessary for biological cells…

Q: you were given an unknown peptide. Explain in detail how you would determine the amino acid sequence…

A: The amino acids that form the protein are mostly L forms. The carboxyl group of amino acids in the…

Q: Can I get a visual (drawn on paper or on a software; like chem draw or chem sketch)? Illustrate…

A: Activation of the SAM:Activate the carboxyl groups using carbodiimide chemistry.Reagents: EDC…

Q: Identify the primary sequence for the polypeptide that yields these fragments upon treatment:…

A: Proteins are the macromolecules composed of amino acids bound together by peptide bond between amino…

Q: "de 96 5 no

A: Answer :- The pH of the solution and the pKa values of the side chains of amino acids must be taken…

Q: draw the structure of the tripeptife Pro-Ser-Cys as it would appear at physiological PH with its…

A: Amino acids can be polymerized to form chains. Peptide bond formation is a condensation reaction in…

Q: Why is methionine (Met) not found on the inside of a protein even though it is hydrophobic?

A: The amino acid methionine is considered as one of the essential amino acids. It is a hydrophobic…

Q: Small molecules are used as inhibitors of protein action - as drugs. They most often do this by…

A: The purpose of this overlay is to compare the binding orientation and interactions of the known…

Q: A particular amino acid contains a -CH2NH3+ group.  Is this amino acid more likely to be found on…

A: In a folded globular protein charged and polar amino acids on the surface of the protein are…

Q: The enzyme creatine kinase catalyzes the ATP-dependent phosphorylation of creatine. Propose a…

A: Introduction:  Creatinine is the waste product formed in muscle from a high-energy storage compound…

Q: In pyrimidine nucleosides, the anti conformation predominates. Explain. Do the purine nucleosides…

A: Introduction and Explanation: Pyrimidines and purines are the nitrogenous bases that are present in…

Q: Consider a hexapeptide of the sequence thr asn glu trp lys gln. A researcher decided that this…

A: The translation is the process of the formation of polypeptide chains of amino acids that lead to…

Q: Given the peptide Val-Ser-Gln-Lys The lateral chain of one of these amino acids can be modified by…

A: During N-terminal acetylation, an acetyl group (CH3-C=O-) is added to the N-terminal amino group…

Q: Calculate the percentage of the peptides synthesized that will be full length and have the correct…

A: The effectiveness of each step i.e. adding of an amino acid residue in Merrifield solid phase…

Osmosis

In simple words, osmosis is the slow, gradual movement of a liquid through a membrane. But there are nuances to this process. For instance, there has to be an imbalance in the distribution of solute in the liquid on either side of the membrane, which has to be semipermeable. The liquid in the region with a lower solute concentration moves to the region with a higher concentration, thereby displacing the solution in the process. The objective is to equalize the concentration of molecules on both sides of the membrane; the displacement of liquid can be viewed as a byproduct of this equalization. Since there is no energy required to carry osmosis, it is considered a passive process.