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Enter numerical values only as you complete the following fill-in-the blanks. The amino acid aspartate has 3 has a charge range of 1 from fully protonated to fully deprotonated) -2 ionizable protons and At pH of 7.4, the net charge of the amino acid aspartate is_ -1 (go

Enter numerical values only as you complete the following fill-in-the blanks. The amino acid aspartate has 3 has a charge range of 1 from fully protonated to fully deprotonated) -2 ionizable protons and At pH of 7.4, the net charge of the amino acid aspartate is_ -1 (go

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Enter numerical values only as you complete the following fill-in-the blanks. The amino acid aspartate has 3 - has a charge range of 1 from fully protonated to fully deprotonated) Ⓡ - -2 ionizable protons and At pH of 7.4, the net charge of the amino acid aspartate is_ -1 . (go
Transcribed Image Text:Enter numerical values only as you complete the following fill-in-the blanks. The amino acid aspartate has 3 - has a charge range of 1 from fully protonated to fully deprotonated) Ⓡ - -2 ionizable protons and At pH of 7.4, the net charge of the amino acid aspartate is_ -1 . (go
Expert Solution
Step 1: Determine the R group of aspartate

Aspartate is an acidic amino acid with R group containing COOH.

It has other functional groups like amino group and carboxyl groups.so there are three ionisable groups in the aspartic acid.

The charge of amino acids d depends on the pH of the surrounding medium.

If the pH is less than the pkA of ionising group, then the group gets protonated.

If the pH is more than the pkA of ionising group , then the group gets deprotonated. 

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