Tryphtophan is an essential amino acid that is used in the biosynthesis of proteins. Its molecular structure is shown below, together with information about the Ka and Kb values of the carboxyl and amine groups in the molecules of this substance. Which of the following forms of this substance is likely to be present in our blood which has a pH close to 7.4? K_= 4.2 x 10-3 HN- NH2 Tryptophan ΟΗ Ko= 2.5x105 ΤΗ HN- NH2 NH3 + HN- NH3+ b) c) d) HN a) NH2 HN-

Biochemistry
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Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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Tryphtophan is an essential amino acid that is used in the biosynthesis of proteins. Its molecular structure is shown below,
together with information about the Ka and Kb values of the carboxyl and amine groups in the molecules of this substance. Which
of the following forms of this substance is likely to be present in our blood which has a pH close to 7.4?
HN-
a)
NH2
ΟΗ
K_= 4.2 x 103
ΤΗ
HN-
NH2
Tryptophan
Ko=2.5x105
HN-
ΟΗ
HN
NH2
NH3+
HN
NH3+
b)
c)
d)
Transcribed Image Text:Tryphtophan is an essential amino acid that is used in the biosynthesis of proteins. Its molecular structure is shown below, together with information about the Ka and Kb values of the carboxyl and amine groups in the molecules of this substance. Which of the following forms of this substance is likely to be present in our blood which has a pH close to 7.4? HN- a) NH2 ΟΗ K_= 4.2 x 103 ΤΗ HN- NH2 Tryptophan Ko=2.5x105 HN- ΟΗ HN NH2 NH3+ HN NH3+ b) c) d)
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