Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
E23. In the Western blot shown here, proteins were isolated from red blood cells and muscle cells from two different individuals. One individual was unaffected, and the other suffered from a disease known as thalassemia, which involves a defect in hemoglobin. The blot was exposed to an antibody that recognizes B globin, which is one of the polypeptides that constitute hemoglobin. Equal amounts of total cellular proteins were added to each lane. Lane 1: Proteins isolated from normal 2 3 4 red blood cells Lane 2: Proteins isolated from the red blood cells of a thalassemia patient Lane 3: Proteins isolated from normal muscle cells Lane 4: Proteins isolated from the muscle cells of a thalassemia patient Explain these results.

E23. In the Western blot shown here, proteins were isolated from red blood cells and muscle cells from two different individuals. One individual was unaffected, and the other suffered from a disease known as thalassemia, which involves a defect in hemoglobin. The blot was exposed to an antibody that recognizes B globin, which is one of the polypeptides that constitute hemoglobin. Equal amounts of total cellular proteins were added to each lane. Lane 1: Proteins isolated from normal 2 3 4 red blood cells Lane 2: Proteins isolated from the red blood cells of a thalassemia patient Lane 3: Proteins isolated from normal muscle cells Lane 4: Proteins isolated from the muscle cells of a thalassemia patient Explain these results.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
See similar textbooks
icon
Related questions
Question
E23. In the Western blot shown here, proteins were isolated from red blood cells and muscle cells from two different individuals. One individual was unaffected, and the other suffered from a disease known as thalassemia, which involves a defect in hemoglobin. The blot was exposed to an antibody that recognizes B globin, which is one of the polypeptides that constitute hemoglobin. Equal amounts of total cellular proteins were added to each lane. Lane 1: Proteins isolated from normal 2 3 4 red blood cells Lane 2: Proteins isolated from the red blood cells of a thalassemia patient Lane 3: Proteins isolated from normal muscle cells Lane 4: Proteins isolated from the muscle cells of a thalassemia patient Explain these results.
Transcribed Image Text:E23. In the Western blot shown here, proteins were isolated from red blood cells and muscle cells from two different individuals. One individual was unaffected, and the other suffered from a disease known as thalassemia, which involves a defect in hemoglobin. The blot was exposed to an antibody that recognizes B globin, which is one of the polypeptides that constitute hemoglobin. Equal amounts of total cellular proteins were added to each lane. Lane 1: Proteins isolated from normal 2 3 4 red blood cells Lane 2: Proteins isolated from the red blood cells of a thalassemia patient Lane 3: Proteins isolated from normal muscle cells Lane 4: Proteins isolated from the muscle cells of a thalassemia patient Explain these results.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON
SEE MORE TEXTBOOKS