these cells are growing in and use it to infect new cells for plaque assays and obtain the following data. toxicity.. You test a newly developed drug against virus #2 in infected cells. You isolate virus from the media 14. Your company is designing a drug to inhibit the replication of this virus and would like to achieve selective 1E+09 100000000 10000000 1000000 100000 10000 1000 100 C. 10 1 Virus #2 a. Replication of DNA -Virus #2 0 10 20 30 40 50 60 70 80 90 100110 mMmMmMmMmMmMmMmMmMmMmMmM Antiviral Concentration For virus #2 which of the following steps of replication could be being inhibited and obtained the data shown? Explain your answer. Also indicate if this is what is being inhibited if you expect to achieve selective toxicity with this drug and why. Plaque forming units/ml b. Production of RNA from a DNA template Production of RNA from an RNA template 10 d. Production of DNA from an RNA template e. Translation of viral proteins by inhibiting cellular ribosomes Gostoving Aa

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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toxicity.. You test a newly developed drug against virus #2 in infected cells. You isolate virus from the media
these cells are growing in and use it to infect new cells for plaque assays and obtain the following data.
14. Your company is designing a drug to inhibit the replication of this virus and would like to achieve selective
1E+09
100000000
10000000
1000000
100000
10000
1000
100
10
1
Virus #2
--Virus #2
0 10 20 30 40 50 60 70 80 90 100110
mMmMmMmMmMmMmMmMmMmMmMmM
a. Replication of DNA
Antiviral Concentration
For virus #2 which of the following steps of replication could be being inhibited and obtained the data shown?
Explain your answer. Also indicate if this is what is being inhibited if you expect to achieve selective toxicity
with this drug and why.
Plaque forming units/ml
b. Production of RNA from a DNA template
c. Production of RNA from an RNA template
10 d. Production of DNA from an RNA template
e. Translation of viral proteins by inhibiting cellular ribosomes
f. How will you test to determine if you are achieving selective toxicity?
vba Avt
Transcribed Image Text:toxicity.. You test a newly developed drug against virus #2 in infected cells. You isolate virus from the media these cells are growing in and use it to infect new cells for plaque assays and obtain the following data. 14. Your company is designing a drug to inhibit the replication of this virus and would like to achieve selective 1E+09 100000000 10000000 1000000 100000 10000 1000 100 10 1 Virus #2 --Virus #2 0 10 20 30 40 50 60 70 80 90 100110 mMmMmMmMmMmMmMmMmMmMmMmM a. Replication of DNA Antiviral Concentration For virus #2 which of the following steps of replication could be being inhibited and obtained the data shown? Explain your answer. Also indicate if this is what is being inhibited if you expect to achieve selective toxicity with this drug and why. Plaque forming units/ml b. Production of RNA from a DNA template c. Production of RNA from an RNA template 10 d. Production of DNA from an RNA template e. Translation of viral proteins by inhibiting cellular ribosomes f. How will you test to determine if you are achieving selective toxicity? vba Avt
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