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Drug: Route: Dose: 3 X F4 Digoxin: Intravenous Bolus - Two Compartment Model Digoxin IV Bolus 0.750 mg Plasma Concentration Time Profile Beta Alpha Time (hrs) Conc (ng/ml) LN (ng/ml) LN (ng/ml) LN 0.00 #NUM! #NUM! #NUM! 0.10 12.290 2.509 #NUM! #NUM! 0.60 6.975 1.942 #NUM! #NUM! 1.00 4.649 1.537 #NUM! #NUM! 2.00 2.201 0.789 #NUM! #NUM! 3.00 1.536 0.429 #NUM! #NUM! 4.00 1.342 0.294 #NUM! #NUM! 5.00 1.273 0.241 #NUM! #NUM! 6.00 1.238 0.213 #NUM! #NUM! 7.00 1.212 0.192 #NUM! #NUM! 8.00 1.188 0.172 #NUM! #NUM! 9.00 1.165 0.153 #NUM! #NUM! 10.00 1.143 0.134 #NUM! #NUM! 11.00 1.122 0.115 #NUM! 12.00 1.101 0.096 #NUM! 13.00 1,080 0.077 #NUM! 16.00 1.020 0.020 #NUM! 24.00 0.876 -0.132 #NUM! Pharmacokinetic Parameters Parameter Value Units A ng/ml Alpha hr-1 B ng/ml Beta hr-1 HC HO CO ng/ml H.C H AUC ng x hr/ml H Vc L OA Vbeta L Vss L CI L/hr TX (alpha) TX (beta) hr days F5 F6 F7 + Digoxin, USP F8 F9 F10 X' F4 O S LN Eptifibatide (ng/ml) 3.00 2.50 2.00 1.50 1.00 0.50 Digoxin IV Bolus - Pharmacokinetics 0.00 -0.50 0 2 4 6 Time (hours) Q+ F5 F6 F7 + 8 10 12 12 400 F8 F9 F10 F11

Drug: Route: Dose: 3 X F4 Digoxin: Intravenous Bolus - Two Compartment Model Digoxin IV Bolus 0.750 mg Plasma Concentration Time Profile Beta Alpha Time (hrs) Conc (ng/ml) LN (ng/ml) LN (ng/ml) LN 0.00 #NUM! #NUM! #NUM! 0.10 12.290 2.509 #NUM! #NUM! 0.60 6.975 1.942 #NUM! #NUM! 1.00 4.649 1.537 #NUM! #NUM! 2.00 2.201 0.789 #NUM! #NUM! 3.00 1.536 0.429 #NUM! #NUM! 4.00 1.342 0.294 #NUM! #NUM! 5.00 1.273 0.241 #NUM! #NUM! 6.00 1.238 0.213 #NUM! #NUM! 7.00 1.212 0.192 #NUM! #NUM! 8.00 1.188 0.172 #NUM! #NUM! 9.00 1.165 0.153 #NUM! #NUM! 10.00 1.143 0.134 #NUM! #NUM! 11.00 1.122 0.115 #NUM! 12.00 1.101 0.096 #NUM! 13.00 1,080 0.077 #NUM! 16.00 1.020 0.020 #NUM! 24.00 0.876 -0.132 #NUM! Pharmacokinetic Parameters Parameter Value Units A ng/ml Alpha hr-1 B ng/ml Beta hr-1 HC HO CO ng/ml H.C H AUC ng x hr/ml H Vc L OA Vbeta L Vss L CI L/hr TX (alpha) TX (beta) hr days F5 F6 F7 + Digoxin, USP F8 F9 F10 X' F4 O S LN Eptifibatide (ng/ml) 3.00 2.50 2.00 1.50 1.00 0.50 Digoxin IV Bolus - Pharmacokinetics 0.00 -0.50 0 2 4 6 Time (hours) Q+ F5 F6 F7 + 8 10 12 12 400 F8 F9 F10 F11

Curren'S Math For Meds: Dosages & Sol
Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 7.10P
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Drug: Route: Dose: 3 X F4 Digoxin: Intravenous Bolus - Two Compartment Model Digoxin IV Bolus 0.750 mg Plasma Concentration Time Profile Beta Alpha Time (hrs) Conc (ng/ml) LN (ng/ml) LN (ng/ml) LN 0.00 #NUM! #NUM! #NUM! 0.10 12.290 2.509 #NUM! #NUM! 0.60 6.975 1.942 #NUM! #NUM! 1.00 4.649 1.537 #NUM! #NUM! 2.00 2.201 0.789 #NUM! #NUM! 3.00 1.536 0.429 #NUM! #NUM! 4.00 1.342 0.294 #NUM! #NUM! 5.00 1.273 0.241 #NUM! #NUM! 6.00 1.238 0.213 #NUM! #NUM! 7.00 1.212 0.192 #NUM! #NUM! 8.00 1.188 0.172 #NUM! #NUM! 9.00 1.165 0.153 #NUM! #NUM! 10.00 1.143 0.134 #NUM! #NUM! 11.00 1.122 0.115 #NUM! 12.00 1.101 0.096 #NUM! 13.00 1,080 0.077 #NUM! 16.00 1.020 0.020 #NUM! 24.00 0.876 -0.132 #NUM! Pharmacokinetic Parameters Parameter Value Units A ng/ml Alpha hr-1 B ng/ml Beta hr-1 HC HO CO ng/ml H.C H AUC ng x hr/ml H Vc L OA Vbeta L Vss L CI L/hr TX (alpha) TX (beta) hr days F5 F6 F7 + Digoxin, USP F8 F9 F10
Transcribed Image Text:Drug: Route: Dose: 3 X F4 Digoxin: Intravenous Bolus - Two Compartment Model Digoxin IV Bolus 0.750 mg Plasma Concentration Time Profile Beta Alpha Time (hrs) Conc (ng/ml) LN (ng/ml) LN (ng/ml) LN 0.00 #NUM! #NUM! #NUM! 0.10 12.290 2.509 #NUM! #NUM! 0.60 6.975 1.942 #NUM! #NUM! 1.00 4.649 1.537 #NUM! #NUM! 2.00 2.201 0.789 #NUM! #NUM! 3.00 1.536 0.429 #NUM! #NUM! 4.00 1.342 0.294 #NUM! #NUM! 5.00 1.273 0.241 #NUM! #NUM! 6.00 1.238 0.213 #NUM! #NUM! 7.00 1.212 0.192 #NUM! #NUM! 8.00 1.188 0.172 #NUM! #NUM! 9.00 1.165 0.153 #NUM! #NUM! 10.00 1.143 0.134 #NUM! #NUM! 11.00 1.122 0.115 #NUM! 12.00 1.101 0.096 #NUM! 13.00 1,080 0.077 #NUM! 16.00 1.020 0.020 #NUM! 24.00 0.876 -0.132 #NUM! Pharmacokinetic Parameters Parameter Value Units A ng/ml Alpha hr-1 B ng/ml Beta hr-1 HC HO CO ng/ml H.C H AUC ng x hr/ml H Vc L OA Vbeta L Vss L CI L/hr TX (alpha) TX (beta) hr days F5 F6 F7 + Digoxin, USP F8 F9 F10
X' F4 O S LN Eptifibatide (ng/ml) 3.00 2.50 2.00 1.50 1.00 0.50 Digoxin IV Bolus - Pharmacokinetics 0.00 -0.50 0 2 4 6 Time (hours) Q+ F5 F6 F7 + 8 10 12 12 400 F8 F9 F10 F11
Transcribed Image Text:X' F4 O S LN Eptifibatide (ng/ml) 3.00 2.50 2.00 1.50 1.00 0.50 Digoxin IV Bolus - Pharmacokinetics 0.00 -0.50 0 2 4 6 Time (hours) Q+ F5 F6 F7 + 8 10 12 12 400 F8 F9 F10 F11
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