4. Multiple Alleles: ABO Blood Types a. Indicate the expected genotype and phenotype ratios for these pairings: i. I^IB x ii Genotype ratio: Phenotype ratio: ii. I^i x I Bi Genotype ratio: Phenotype ratio: b. (True/False) A type O child may have two type A parents. A type O child may have one type AB parent. A type B child may have two type AB parents. A type AB child may have one type O parent. c. Ana (type A, Rht blood) is suing James (type AB, Rh blood) for child support claiming that he is the father of her child (type B, Rh+ blood). On the basis of blood type, is it possible that James is the father? What ABO blood type(s) would James have to possess to prove that is not the father? 5. Dihybrid Crosses with Dominance a. Determine the predicted phenotype ratio in children of dihybrid (heterozygous) parents that are both right-handed and possess free earlobes. Parent phenotypes Parent genotypes Gametes Punnett Square Phenotype Ratio right-handed free earlobes right-handed attached earlobes left-handed free earlobes left-handed attached earlobes 17

4. Multiple Alleles: ABO Blood Types a. Indicate the expected genotype and phenotype ratios for these pairings: i. I^IB x ii Genotype ratio: Phenotype ratio: ii. I^i x I Bi Genotype ratio: Phenotype ratio: b. (True/False) A type O child may have two type A parents. A type O child may have one type AB parent. A type B child may have two type AB parents. A type AB child may have one type O parent. c. Ana (type A, Rht blood) is suing James (type AB, Rh blood) for child support claiming that he is the father of her child (type B, Rh+ blood). On the basis of blood type, is it possible that James is the father? What ABO blood type(s) would James have to possess to prove that is not the father? 5. Dihybrid Crosses with Dominance a. Determine the predicted phenotype ratio in children of dihybrid (heterozygous) parents that are both right-handed and possess free earlobes. Parent phenotypes Parent genotypes Gametes Punnett Square Phenotype Ratio right-handed free earlobes right-handed attached earlobes left-handed free earlobes left-handed attached earlobes 17

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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1. Study the given alleles. Write the correct phenotype for each genotype. X– normal Genotype XC – Color-blind Phenotype XX XY XCXC www m XX www w ww w 2. Study the given alleles. Write the correct genotype for each phenotype. X- normal Genotype хн- Hemophiliaс Phenotype Hemophiliac female Hemophiliac male Normal female carrier of the gene Normal male Normal female
A. For the following genotypes state the ABO blood phenotype. JAJA |B|O_ 101⁰_ |A|B_ B. Using genetic diagrams, show how it is possible for a couple with a type A mother and a type B father can have a child with type O blood. C. Using genetic diagrams show how a type AB person with a type O partner have offspring that share neither of their phenotypes.
4. Attached earlobes are dominant over free hanging earlobes. Complete the Punnett Square for the following individuals: Mom-Bb and Dad=bb Provide the genotype and phenotype ratios using the Punnett square given below. Genotypes 5. When two alleles are observed independently in a phenotype is called multiple alleles. Human blood group ABO is a good example of multiple alleles. The three alleles are: IA, IB, i. Mother's blood type is AB (IAI³) and father's blood type is B (I³i). Provide the genotype and phenotype ratios using the Punnett square given below. Genotypes Phenotypes Genotypes Phenotypes 6. When the allele of a trait is found on X or Y chromosome, it becomes sex-linked. The results differ from males to females. One such example is of red green colorblindness. The mother is a carrier (X© Xº ), and the father is colorblind (X© Y). Provide the genotype and phenotype ratios using the Punnett square given below. Phenotypes
16.A couple is suspecting that their baby was switched at the hospital. The mother has blood type A, the father has blood type B, and the baby has blood type O. Which among the following conditions would prove that the baby is switched? A. Mother’s genotype: IAIA & Father’s genotype: ii B. Mother’s genotype: ii & Father’s genotype: IBIB C. Mother’s genotype: IAIA & Father’s genotype: IBIB D. Mother’s genotype: IAi & Father’s genotype: IBi
1. In humans, hemophilia is a sex linked trait. Females can be normal, carriers, or have the disease. Males will have the disease or not (but they won't be ever carriers) XH XH = female, normal XH Xh = female, carrier Xh Xh = female, hemophilic XH Y = male, normal Xh Y = male, hemophilic a) Show the cross of a man who has hemophilia with a woman who is a carrier. b) What is the probability that their children have the disease
5. A woman with type AB blood marries a man with type homozygous type B blood. What are the phenotype and genotype ratios of the offspring? 6. Hemophilia is a sex linked recessive trait. If a carrier woman marries a normal man. The couple gives birth to a boy. What are the chances that this child will have hemophilia? Make sure use XX or XY here) 7. The height of a certain plant is a result of polygenic inheritance involving two pairs of genes. Draw a Punnett square to show the result of a cross between a tall (AABB) plant and a short (aabbi. What is the phenotype ratio? 8. What is a mutation? 9. What is sickle cell anemia? 10. What is hemophilia? 11. What is a pedigree? 12. Draw a pedigree to represent the following. Shaded symbols should represent individuals with hemophilia: A man with hemophilia marries a normal woman. They have 3 children, two normal boys and a girl who is a carrier. The girl marries a normal man and they have two boys and two girls. One of the girls is a carrier…
3. What are the genotypes possible for a person who has: A blood? B blood? O blood? AB blood? 4. A man with type AB blood is married to a woman also with type AB blood. Show the cross. What proportion of their children will have: A blood? B blood? O blood? AB blood? 5. A man has type B blood (genotype I³I®) is married to a woman with type O (ii) blood. Show the cross. What proportion of their children will have: 1. A blood? 2. B blood? 3. O blood? 4. AB blood? 6. A woman with type A blood (genotype I^i) is married to a type B person (genotype Iºi). Show the cross. What proportion of their children will have: A blood? B blood? О blood? AB blood?
6. A man with type B blood marries a woman with type A blood. They have the first child with bloodtype O.a. What are the genotypes of the father and the mother?b. What is the genotype and phenotype of the baby? 7. A man with type O blood marries a woman with type AB blood. What is the predicted genotypicand phenotypic ratios of their children?
d Dd 501. s0% 5. Another type of blood disorder is hemophilia, which is an X linked disorder caused by a recessive allele. Like VWD, this disorder interferes with the protein that is involved with blood clotting. Known as "bleeder's disease" because any minor injury can become life threatening. This disorder is considered more severe than VWD. In both cases there are versions of the disorder that can be less and more severe depending on which protein or clotting factor is affected. Normal XHY Normal X"Xh Carrier XhY Hemophilia Bourthelesm X"Xh Hemophilia If a woman is a carrier, what percentage of her SONS will have the disorder? How many (%) of their sons will have hemophilia? How many (%) of their sons will be normal? How many (%) of their daughters will be normal? 6. A man who has hemophilia marries a normal woman (not a carrier)... How many (%) of their sons will have hemophilia? How many (%) of their daughters will be carriers 7. A woman who is a carrier marries a man with…
1. Hemophilia is due to a sex-linked gene. It is recessive and found on the X chromosome. A woman who is a carrier for hemophilia marries a normal man. What will be the possible phenotypes of their children? Use a punnet square. 2. A phenotypically normal man, who has a hemophiliac brother, marries a normal woman, who is not a carrier. What is the probability that any of their children will be hemophiliac? Use a punnet square. 3. Color-blindness is an X-linked, recessive trait. If a normal-sighted woman, whose father was color-blind, marries a colorblind man, what is the probability that they will have a son who is color-blind? Use a punnet square. 4. A man and woman, both of normal vision, have: 1) a color-blind son (#1) who has a daughter of normal vision 2) a daughter (#1) of normal vision who has one color-blind son and one normal vision son 3) another daughter (#2) of normal vision who has five sons, all with normal vision What are the probable genotypes of the…
. Assuming no involvement of the Bombay phenotype(in case you’ve already read ahead to Section 3.2):a. If a girl has blood type O, what could be the genotypes and corresponding phenotypes of her parents?b. If a girl has blood type B and her mother has bloodtype A, what genotype(s) and correspondingphenotype(s) could the other parent have?c. If a girl has blood type AB and her mother is alsoAB, what are the genotype(s) and correspondingphenotype(s) of any male who could not be thegirl’s father?
V. Two Gene Pairs (Extra Credit) 1... A. In peas, the allele for tall plants (T) is dominant over the allele for short plants (t). The allele for smooth peas (S) is dominant over the allele for wrinkled peas (s). Use this information to cross the following parents. I 1. heterozygous tall and smooth X heterozygous tall and smooth 2. heterozygous tall, wrinkled X short, wrinkled AL.