Consider one of the reactions of the citric acid cycle shown below Malate + NAD+ ⇆ Oxaloacetate + NADH + H+ (malate dehydrogenase) ΔG˚′ = +29.7 kJ/mol. Describe two factors that allow this thermodynamically unfavorable reaction to occur in the direction of malate to oxaloacetate.

Consider one of the reactions of the citric acid cycle shown below Malate + NAD+ ⇆ Oxaloacetate + NADH + H+ (malate dehydrogenase) ΔG˚′ = +29.7 kJ/mol. Describe two factors that allow this thermodynamically unfavorable reaction to occur in the direction of malate to oxaloacetate.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter25: Nitrogen Acquisition And Amino Acid Metabolism

Section: Chapter Questions

Problem 22P

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Question

Consider one of the reactions of the citric acid cycle shown below

Malate + NAD⁺ ⇆ Oxaloacetate + NADH + H⁺(malate dehydrogenase) ΔG˚′ = +29.7 kJ/mol.

Describe two factors that allow this thermodynamically unfavorable reaction to occur in the direction of malate to oxaloacetate.

Science that deals with the amount of energy transferred from one equilibrium state to another equilibrium state.

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