A series of hybrid cell lines was created by somatic human-mouse somatic cell hybridization. Each cell line (numbers 7, 12, 17, 28, and 32) was examined for the presence of human chromosomes and for the ability to produce an enzyme. The fresults shown below were obtained. On the basis of these results, which human chromosome has the gene that encodes the enzyme? Human Chromosomes Present 2 3 Cell Line 6 8 9 Enzyme production 1 4 5 7 10 Yes 12 Yes 17 Yes 28 No 32 Yes

A series of hybrid cell lines was created by somatic human-mouse somatic cell hybridization. Each cell line (numbers 7, 12, 17, 28, and 32) was examined for the presence of human chromosomes and for the ability to produce an enzyme. The fresults shown below were obtained. On the basis of these results, which human chromosome has the gene that encodes the enzyme? Human Chromosomes Present 2 3 Cell Line 6 8 9 Enzyme production 1 4 5 7 10 Yes 12 Yes 17 Yes 28 No 32 Yes

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Please consider the figure below, parts A and B. A В Gene B Gene C Gene B Normal Gene A Chromosome 12 Normal Chromosome 1 Please consider figure A. a. Do these chromosomes come from a dividing or non-dividing cell? Give a reason for your answer. b. How many molecules of double stranded DNA will be present at anaphase I of a cell from this organism? Please consider figure B. A potentially carcinogenic mutation occurred on one of the chromosomes. The gene affected by the mutation codes for a protein involved in the repair of DNA damage. c. What is the correct term used to describe this chromosomal mutation? d. In terms of the development of cancer, is this a dominant or recessive mutation? e. What is the consequence of this mutation if it occurs during meiosis and is inherited by the offspring? Explain your answer in terms of the function of the protein.
Three linked genes (v, p and b) are studied to begin a genetic map. Crosses were carried out and 10,000 progeny were analyzed for each cross. Of 10,000 progeny, there were: 2207 recombinants between v and p 1489 recombinants between p and b 718 recombinants between b and v Use this information to determine the order of these genes on the chromosome (i.e. construct a genetic map)
Show the exact location of the following gene in the chromosome. Draw and label. 2p32.1 2q42.2 2p21.3 2q12.3 2p11.2
A line of mouse cells is grown for many generations in a medium with 15N. Cells in G1 are then switched to a new medium that contains 14N. Draw a pair of homologous chromosomes from these cells at the following stages, showing the two strands of DNA molecules found in the chromosomes. Use different colors to represent strands with 14N and 15N. a. Cells in G1, before switching to medium with 14N b. Cells in G2, after switching to medium with 14N c. Cells in anaphase of mitosis, after switching to medium with 14N d. Cells in metaphase I of meiosis, after switching to medium with 14N e. Cells in anaphase II of meiosis, after switching to medium with 14N
. A diploid strain of yeast was made by mating a haploidstrain with a genotype w−, x−, y−, and z− with a haploidstrain of opposite mating type that is wild type for thesefour genes. The diploid strain was phenotypically wildtype. Four different X-ray-induced diploid mutantswith the following phenotypes were produced fromthis diploid yeast strain. Assume a single new mutation is present in each strain.Strain 1 w− x+ y− z+Strain 2 w+ x− y− z−Strain 3 w− x+ y− z−Strain 4 w− x+ y+ z+When these mutant diploid strains of yeast go throughmeiosis, each ascus is found to contain only two viablehaploid spores.a. What kind of mutations were induced by X-rays tomake the listed diploid strains?b. Why did two spores in each ascus die?c. Are any of the genes w, x, y, or z located on thesame chromosome?d. Give the order of the genes that are found on thesame chromosome
why does a clone of cells produceonly one type of G-6-PD enzyme? What would you expect to happen if a clone was derived from an early embryonic cell? Whydoes the initial sample of tissue produce both forms of G-6-PD?
In a genetic laboratory, a plant species was subjected to radiation to produce chromosome mutations. The mutated plant was then inbred for many generations until it was true breeding for all of these mutations. It was then crossed to the original non-mutated plant, and the meiotic process of the F1 hybrids was examined. In the examination, a cell with a dicentric chromosome and an acentric fragment was noticed in anaphase I of the hybrid. (i) What kind of chromosomal mutation occurred in the irradiated plant? In your answer, indicate the position of the centromere. (ii) Diagram the alignment of the chromosomes during meiosis. Assume that the gene sequence in the original unirradiated plant is AB//CDEFGHIJK and the inverted region involved genes DEFGHI (double strokes indicate the position of the centromere). (ii) Diagram the results of a single crossover between homologous gene E and F in the inversion.
n yeast cells, telomerase remains active and maintains telomeres of about 300 base pairs. Propose what would happen to the telomeres over time in a yeast lineage in which the following mutations were created. The gene encoding the catalytic subunit of the telomerase is deleted.
The image below shows a standard human karyotype, from a metaphase cell. Note that the positioning of the chromosomes in the image is to aid visualization; they are not lined up this way in the cell. Вох 1 Вох 2 5 器 1 88 9 10 11 12 13 14 15 16 17 18 19 20 21 22 2012 Pearson Education, he If this individual is heterozygous for a gene on chromosome 1, with alleles A and a, what alleles could be represented in the chromosomes in Box 1? Select all that are correct. Assume that the image represents a mitotic cell. a. A only b. a only c. Both A and a
Which of the following patterns was observed, in the experiments of Hershey and Chase, using the T2 bacteriophage of E. coli? radioactive proteins were passed on to viral progeny, but not radioactive polynucleotides radioactive polynucleotides were passed on to viral progeny, but not radioactive proteins both radioactive proteins and radioactive polynucleotides were passed on to viral progeny both radioactive polynucleotides and radioactive proteins were passed on to viral progeny neither radioactive proteins nor radioactive polynucleotides were passed on to viral progeny
This diagram shows a parental cell going through mitosis and producing 2 daughter cells. Which cells in th- mutation.) D |G H) D and G are genetically identical, but H is genetically different. O D and H are genetically identical, but G is genetically different. O Gand H are genetically identical, but D is genetically different. O All of the cells - D, G, and H - are genetically identical. O None of the cells in the diagram are genetically identical. All the cells - D, G, and H- are genetically different from each otl
The image below shows a standard human karyotype, from a metaphase cell. Note that the positioning of the chromosomes in the image is to aid visualization; they are not lined up this way in the cell. Вох 1 Вох 2 3 88 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 © 2012 Pearson Education, Inc. If the image represents a meiotic cell, what will happen to the DNA represented in Box 1 after meiosis is complete? а. It will be split equally between the four daughter cells. Ob. It will be split between two of the four daughter cells, with different amounts of DNA in each cell. O c. It will be split between two of the four daughter cells, with the same amounts of DNA in each cell. d It will all end up in one daughter cell.