One way that researchers create a cell line that is "immortal" (divides forever in culture) is by introducing DNA that forces the cell to express telomerase. Why do cells that don't express the telomerase protein stop dividing? What specifically goes wrong?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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One way that researchers create a cell line that is "immortal" (divides forever in culture) is by introducing DNA that forces the cell to express telomerase. Why do cells that don't express the telomerase protein stop dividing? What specifically goes wrong?

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Introduction:

Telomeres are repetitive sequences of DNA that are present at the ends of the chromosomes and help maintain the integrity of the chromosomes. However, with each cell division, the length of these repetitive sequences diminishes leading to aging and finally death.

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