Which of the following statements regarding DNA synthesis at the ends of linear chromosomes i Eruel Because DNA polymerase has proofreading capabilities, replication at the ends of linear chromosomes is Lsally error-free, and telomerase, an enzyme composed of both RNA and protein, simply ensures that any incorporated errors are corrected. O DNA synthesis at the ends of linear chromosomes is a problem also observed in prokaryotic cells. O I, Because DNA polymerase is not able to initlate strand synthesis, linear chromosomes will have a 3' overhang at their ends. This is corrected by telomerase, an enzyme composed of both RNA and protein, which extends the ends of eukaryotic chromosomes y Cancer in humans is associated with a reduction in the activity of telomerase. y Telomerase, an enzyme composed of both RNA and protein, fünctions by cleaving the 3 overhangs that are left by DNA polymerase.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Which of the following statements regarding DNA Synthesis at the ends of linear chromosomes is true?
Because DNA polymerase has proofreading capablities, replication at the ends of linear chromosomes is usually error-free, and telomerase, an enzyme composed of both RNA and protein, simply ensures that any incorporated errors are corrected.
O DNA synthesis at the ends of linear chromosomes is a problem also observed in prokaryotic cells.
Ov. Cancer in humans is associated with a reduction in the activity of telomerase.
y Telomerase, an enzyme composed of both RNA and protein. fünctions by cleaving the 3 overhangs that are left by DNA polymerase.
Transcribed Image Text:Which of the following statements regarding DNA Synthesis at the ends of linear chromosomes is true? Because DNA polymerase has proofreading capablities, replication at the ends of linear chromosomes is usually error-free, and telomerase, an enzyme composed of both RNA and protein, simply ensures that any incorporated errors are corrected. O DNA synthesis at the ends of linear chromosomes is a problem also observed in prokaryotic cells. Ov. Cancer in humans is associated with a reduction in the activity of telomerase. y Telomerase, an enzyme composed of both RNA and protein. fünctions by cleaving the 3 overhangs that are left by DNA polymerase.
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