The homologous chromosome pairs in our cells do not carry identical sequences in all loci. This heterozygosity (difference between the two.copies) can be altered in cancer: in fact, loss of heterozygosity at many loci is observed in cancer cells, through an increase in either homozygosity (two identical copies) or hemizygosity (e. loss of one copy). Researchers can take advantage of this loss of heterozygosity in cancer cells to identify genomic loci that contain cancer-critical genes. What type of gene would you expect to find in chromosomal regions with a loss of heterozygosity? Proto-oncogenes or tumour suppressor genes? Choose the correct answer here Proto-oncogenes Tumour Suppressor genes

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The homologous chromosome pairs in our cells do not carry identical sequences in all loci. This heterozygosity (difference between the two.copies) can be altered in cancer: in fact, loss of heterozygosity at many loci is
observed in cancer cells, through an increase in either homozygosity (two identical copies) or hemizygosity (i.e. loss of one copy). Researchers can take advantage of this loss of heterozygosity in cancer cells to identify
genomic loci that contain cancer-critical genes. What type of gene would you expect to find in chromosomal regions with a loss of heterozygosity? Proto-oncogenes or tumour suppressor genes?
Choose the correct answer here
Proto-oncogenes
Tumour Suppressor genes
Transcribed Image Text:The homologous chromosome pairs in our cells do not carry identical sequences in all loci. This heterozygosity (difference between the two.copies) can be altered in cancer: in fact, loss of heterozygosity at many loci is observed in cancer cells, through an increase in either homozygosity (two identical copies) or hemizygosity (i.e. loss of one copy). Researchers can take advantage of this loss of heterozygosity in cancer cells to identify genomic loci that contain cancer-critical genes. What type of gene would you expect to find in chromosomal regions with a loss of heterozygosity? Proto-oncogenes or tumour suppressor genes? Choose the correct answer here Proto-oncogenes Tumour Suppressor genes
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