An STR on chromosome 5 is very closely linked to a gene involved in a dominant metabolism disorder (one one copy of the mutation causes the disease). There are four different alleles of the STR (Q, B, S, and L), each with different numbers of GATCTCG repeats. The S allele has 2 repeats, the B allele has 7 repeats, the Q allele has 10 repeats, and the L allele has 5 repeats. Part 1 Lane 1 of the gel shown below indicates the locations of PCR products corresponding to all four STR alleles when run together in one lane. DNA was loaded into the wells at the top of the gel. Move the letter of each allele to its correct position at the left of Lane 1 to indicate where each allele runs on the gel. Gabriel Lane 1 Andre O Maria Andre Maria Juliana Gabriel Camila B Part 2 Andre and Maria are the parents in this family; all others shown on the gel are children. Daughter Juliana is born with the metabolism disorder, but daughter Camila does not have the disorder. Assuming no recombination between the STR marker and the metabolic disease mutation, who else in the family has the disorder? L S Q Part 3 Why does Gabriel have only one band on the gel? O He inherited an allele from only one parent. O He inherited the same allele from each parent. O The DNA must have run incorrectly.

Name: An STR on chromosome 5 is very closely linked to a gene involved in a
Uploaded: 2024-03-20T06:42:55.000Z
Channel: Bartleby
Description: An STR on chromosome 5 is very closely linked to a gene involved in a dominant metabolism disorder (one one copy of the mutation causes the disease). There are four different alleles of the STR (Q, B, S, and L), each with different numbers of GATCTC